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Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 10,Page: 1279-1291
Authors:  Lei Fan;  Xiao-xia Qiu;  Zhi-yuan Zhu;  Jian-lu Lv;  Jian Lu;  Fei Mao;  Jin Zhu;  Jia-ying Wang;  Xiao-wei Guan;  Jing Chen;  Jin Ren;  Ji-ming Ye;  Yong-hua Zhao;  Jian Li;  Xu Shen
Favorite | View/Download:23/0 | TC[WOS]:2 TC[Scopus]:8 | Submit date:2020/04/14
App/ps1 Transgenic Mice  Alzheimer’s Disease  Autophagy  Inflammation  Nitazoxanide  
Deciphering the Pharmacological Mechanisms of the Huayu-Qiangshen-Tongbi Formula Through Integrating Network Pharmacology and In Vitro Pharmacological Investigation Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Zihao Wang;  Ke-Gang Linghu;  Yuanjia Hu;  Huali Zuo;  Hao Yi;  Shi-Hang Xiong;  Jinjian Lu;  Ging Chan;  Hua Yu;  Run-Yue Huang
Favorite | View/Download:31/0 | TC[WOS]:1 TC[Scopus]:4 | Submit date:2019/12/04
Rheumatoid Arthritis  Network Pharmacology  Traditional Chinese Medicine  Huayu-qiangshen-tongbi Formula  In Vitro Validation  
Yinchenhao decoction suppresses rat liverfibrosis involved in an apoptosisregulation mechanism based on network pharmacology and transcriptomicanalysis Journal article
Biomedicine & Pharmacotherapy, 2019,Volume: 114
Authors:  Fei-Fei Cai;  Yan-Qin Bian;  Rong Wu;  Yang Sun;  Xiao-Le Chen;  Meng-Die Yang;  Qian-ru Zhang;  Yuanjia Hu;  Ming-Yu Sun;  Shi-Bing Su
Favorite | View/Download:11/0 | TC[WOS]:17 TC[Scopus]:19 | Submit date:2020/10/23
Yinchenhao Decoction  Liver Fibrosis  Network Pharmacology  Transcriptomics  Apoptosis  
Upregulation of phosphoserine phosphatase contributes to tumor progression and predicts poor prognosis in non-small cell lung cancer patients Journal article
THORACIC CANCER, 2019,Volume: 10,Issue: 5,Page: 1203-1212
Authors:  Li Liao;  Huajian Yu;  Mengxi Ge;  Qiong Zhan;  Ruofan Huang;  Xiaoyu Ji;  Xiaohua Liang;  Xinli Zhou
Favorite | View/Download:20/0 | TC[WOS]:0 TC[Scopus]:2 | Submit date:2020/03/10
Akt/ampk Signaling Pathway  Metastasis  Nsclc  Proliferation  Psph  
Combined treatment of sodium ferulate, n-butylidenephthalide, and ADSCs rehabilitates neurovascular unit in rats after photothrombotic stroke Journal article
Journal of Cellular and Molecular Medicine, 2019,Volume: 23,Issue: 1,Page: 126-142
Authors:  Zhao Y.-H.;  Liu N.-W.;  Ke C.-C.;  Liu B.-W.;  Chen Y.-A.;  Luo C.;  Zhang Q.;  Xia Z.-Y.;  Liu R.-S.
Favorite | View/Download:27/0 | TC[WOS]:1 TC[Scopus]:2 | Submit date:2019/01/15
Adipose-derived Stromal Cells  N-butylidenephthalide  Neurovascular Unit  Rehabilitation  Sodium Ferulate  
Benzofurans from Eupatorium chinense enhance insulin-stimulated glucose uptake in C2C12 myotubes and suppress inflammatory response in RAW264.7 macrophages Journal article
Fitoterapia, 2019,Volume: 134,Page: 346-354
Authors:  Jiang-HuanKe;  Li-ShaZhang;  Shi-XinChen;  Sheng-NanShen;  TianZhang;  Chang-XinZhou;  Jian-XiaMo;  Li-GenLin;  Li-SheGan
Favorite | View/Download:22/0 | TC[WOS]:3 TC[Scopus]:5 | Submit date:2020/03/20
Glucose Uptake  Benzofuran  Eupatorium Chinense  Quantum Chemical Calculation  Anti-inflammation  
OTUB2 stabilizes U2AF2 to promote the Warburg effect and tumorigenesis via the AKT/mTOR signaling pathway in non-small cell lung cancer Journal article
THERANOSTICS, 2019,Volume: 9,Issue: 1,Page: 179-195
Authors:  Jing Li;  Dongdong Cheng;  Miaoxin Zhu;  Huajian Yu;  Zhen Pan;  Lei Liu;  Qin Geng;  Hongyu Pan;  Mingxia Yan;  Ming Yao
Favorite | View/Download:22/0 | TC[WOS]:11 TC[Scopus]:20 | Submit date:2020/03/11
Deubiquitinating Enzyme  Otub2  Nsclc  Warburg Effect  U2af2  
Rapid identification of antimicrometastases drugs using integrated model systems with two dimensional monolayer, three dimensional spheroids, and zebrafish xenotransplantation tumors Journal article
BIOTECHNOLOGY AND BIOENGINEERING, 2018,Volume: 115,Issue: 11,Page: 2828-2843
Authors:  Fu, Afu;  Peh, Yu Ming;  Ngan, Weida;  Wei, Na;  Luo, Kathy Qian
Favorite | View/Download:19/0 | TC[WOS]:2 TC[Scopus]:6 | Submit date:2019/01/17
antimetastasis drug discovery  fluorescence resonance energy transfer  PI3K  AKT pathway  three dimensional tumor spheroids  zebrafish xenograft tumor model  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View | Adobe PDF | Favorite | View/Download:848/46 | TC[WOS]:4 TC[Scopus]:11 | Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
View | Adobe PDF | Favorite | View/Download:1442/102 | TC[WOS]:3 TC[Scopus]:5 | Submit date:2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation