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Rmrp Mutation Disrupts Chondrogenesis and Bone Ossification in Zebrafish Model of Cartilage-Hair Hypoplasia via Enhanced Wnt/β-Catenin Signaling Journal article
Journal of Bone and Mineral Research, 2019,Volume: 34,Issue: 11,Page: 2101-2116
Authors:  Sun，Xianding;  Zhang，Ruobin;  Liu，Mi;  Chen，Hangang;  Chen，Liang;  Luo，Fengtao;  Zhang，Dali;  Huang，Junlan;  Li，Fangfang;  Ni，Zhenhong;  Qi，Huabing;  Su，Nan;  Jin，Min;  Yang，Jing;  Tan，Qiaoyan;  Du，Xiaolan;  Chen，Bo;  Huang，Haiyang;  Chen，Shuai;  Yin，Liangjun;  Xu，Xiaoling;  Deng，Chuxia;  Luo，Lingfei;  Xie，Yangli;  Chen，Lin
Favorite | View/Download：76/0 | TC[WOS]:2 TC[Scopus]:4 | Submit date：2020/09/16
CARTILAGE-HAIR HYPOPLASIA  RMRP  SKELETAL DEVELOPMENT  WNT/Β-CATENIN  ZEBRAFISH  
Andrographolide derivative ameliorates dextran sulfate sodium-induced experimental colitis in mice Journal article
BIOCHEMICAL PHARMACOLOGY, 2019,Volume: 163,Page: 416-424
Authors:  Bao-Jian Guo;  Zhuyun Liu;  Mo-Yu Ding;  Feng Li;  Mei Jing;  Li-Peng Xu;  Yu-Qiang Wang;  Zai-Jun Zhang;  Yitao Wang;  Decai Wang;  Guo-Chun Zhou;  Ying Wang
Favorite | View/Download：23/0 | TC[WOS]:2 TC[Scopus]:3 | Submit date：2020/03/27
Andrographolide Analog  Colitis  Ibd  Nf-κb  Β-catenin  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View | Adobe PDF | Favorite | View/Download：848/46 | TC[WOS]:4 TC[Scopus]:11 | Submit date：2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
GSK3-activated STAT5 regulates expression of SFRPs to modulate adipogenesis Journal article
FASEB JOURNAL, 2018,Volume: 32,Issue: 9,Page: 4714-4726
Authors:  Wang, Li;  Wang, Yuan;  Meng, Yuan;  Zhang, Chao;  Di, Lijun
Favorite | View/Download：1629/0 | TC[WOS]:8 TC[Scopus]:11 | Submit date：2018/10/30
Adipocyte Differentiation  Gsk3  Wnt Pathway  
DJ-1 promotes colorectal cancer progression through activating PLAGL2/Wnt/BMP4 axis Journal article
CELL DEATH & DISEASE, 2018,Volume: 9
Authors:  Zhou, Jing;  Liu, Hao;  Zhang, Lian;  Liu, Xin;  Zhang, Chundong;  Wang, Yitao;  He, Qing;  Zhang, Ying;  Li, Yi;  Chen, Quanmei;  Zhang, Lu;  Wang, Kui;  Bu, Youquan;  Lei, Yunlong
Favorite | View/Download：29/0 | TC[WOS]:14 TC[Scopus]:20 | Submit date：2018/11/01
Oncogenic Signaling Pathways in The Cancer Genome Atlas Journal article
Cell, 2018,Volume: 173,Issue: 2,Page: 321-337.e10
Authors:  Sanchez-Vega F.;  Mina M.;  Armenia J.;  Chatila W.K.;  Luna A.;  La K.C.;  Dimitriadoy S.;  Liu D.L.;  Kantheti H.S.;  Saghafinia S.;  Chakravarty D.;  Daian F.;  Gao Q.;  Bailey M.H.;  Liang W.-W.;  Foltz S.M.;  Shmulevich I.;  Ding L.;  Heins Z.;  Ochoa A.;  Gross B.;  Gao J.;  Zhang H.;  Kundra R.;  Kandoth C.;  Bahceci I.;  Dervishi L.;  Dogrusoz U.;  Zhou W.;  Shen H.;  Laird P.W.;  Way G.P.;  Greene C.S.;  Liang H.;  Xiao Y.;  Wang C.;  Iavarone A.;  Berger A.H.;  Bivona T.G.;  Lazar A.J.;  Hammer G.D.;  Giordano T.;  Kwong L.N.;  McArthur G.;  Huang C.;  Tward A.D.;  Frederick M.J.;  McCormick F.;  Meyerson M.;  Caesar-Johnson S.J.;  Demchok J.A.;  Felau I.;  Kasapi M.;  Ferguson M.L.;  Hutter C.M.;  Sofia H.J.;  Tarnuzzer R.;  Wang Z.;  Yang L.;  Zenklusen J.C.;  Zhang J.J.;  Chudamani S.;  Liu J.;  Lolla L.;  Naresh R.;  Pihl T.;  Sun Q.;  Wan Y.;  Wu Y.;  Cho J.;  DeFreitas T.;  Frazer S.;  Gehlenborg N.;  Getz G.;  Heiman D.I.;  Kim J.;  Lawrence M.S.;  Lin P.;  Meier S.;  Noble M.S.;  Saksena G.;  Voet D.;  Zhang H.;  Bernard B.;  Chambwe N.;  Dhankani V.;  Knijnenburg T.;  Kramer R.;  Leinonen K.;  Liu Y.;  Miller M.;  Reynolds S.;  Shmulevich I.;  Thorsson V.;  Zhang W.;  Akbani R.;  Broom B.M.;  Hegde A.M.;  Ju Z.;  Kanchi R.S.;  Korkut A.;  Li J.;  Liang H.;  Ling S.;  Liu W.;  Lu Y.;  Mills G.B.;  Ng K.-S.;  Rao A.;  Ryan M.;  Wang J.;  Weinstein J.N.;  Zhang J.;  Abeshouse A.;  Armenia J.;  Chakravarty D.;  Chatila W.K.;  de Bruijn I.;  Gao J.;  Gross B.E.;  Heins Z.J.;  Kundra R.;  La K.;  Ladanyi M.;  Luna A.;  Nissan M.G.;  Ochoa A.;  Phillips S.M.;  Reznik E.;  Sanchez-Vega F.;  Sander C.;  Schultz N.;  Sheridan R.;  Sumer S.O.;  Sun Y.;  Taylor B.S.;  Wang J.;  Zhang H.;  Anur P.;  Peto M.;  Spellman P.;  Benz C.;  Stuart J.M.;  Wong C.K.;  Yau C.;  Hayes D.N.;  Parker J.S.;  Wilkerson M.D.;  Ally A.;  Balasundaram M.;  Bowlby R.;  Brooks D.;  Carlsen R.;  Chuah E.;  Dhalla N.;  Holt R.;  Jones S.J.M.;  Kasaian K.;  Lee 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J.J.;  Owonikoko T.;  Pickens A.;  Ramalingam S.;  Shin D.M.;  Sica G.;  Van Meir E.G.;  Zhang H.;  Eijckenboom W.;  Gillis A.;  Korpershoek E.;  Looijenga L.;  Oosterhuis W.;  Stoop H.;  van Kessel K.E.;  Zwarthoff E.C.;  Calatozzolo C.;  Cuppini L.;  Cuzzubbo S.;  DiMeco F.;  Finocchiaro G.;  Mattei L.;  Perin A.;  Pollo B.;  Chen C.;  Houck J.;  Lohavanichbutr P.;  Hartmann A.;  Stoehr C.;  Stoehr R.;  Taubert H.;  Wach S.;  Wullich B.;  Kycler W.;  Murawa D.;  Wiznerowicz M.;  Chung K.;  Edenfield W.J.;  Martin J.;  Baudin E.;  Bubley G.;  Bueno R.;  De Rienzo A.;  Richards W.G.;  Kalkanis S.;  Mikkelsen T.;  Noushmehr H.;  Scarpace L.;  Girard N.;  Aymerich M.;  Campo E.;  Gine E.;  Guillermo A.L.;  Van Bang N.;  Hanh P.T.;  Phu B.D.;  Tang Y.;  Colman H.;  Evason K.;  Dottino P.R.;  Martignetti J.A.;  Gabra H.;  Juhl H.;  Akeredolu T.;  Stepa S.;  Hoon D.;  Ahn K.;  Kang K.J.;  Beuschlein F.;  Breggia A.;  Birrer M.;  Bell D.;  Borad M.;  Bryce A.H.;  Castle E.;  Chandan 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L.;  Dinkin M.;  Manikhas G.;  Alvaro D.;  Bragazzi M.C.;  Cardinale V.;  Carpino G.;  Gaudio E.;  Chesla D.;  Cottingham S.;  Dubina M.;  Moiseenko F.;  Dhanasekaran R.;  Becker K.-F.;  Janssen K.-P.;  Slotta-Huspenina J.;  Abdel-Rahman M.H.;  Aziz D.;  Bell S.;  Cebulla C.M.;  Davis A.;  Duell R.;  Elder J.B.;  Hilty J.;  Kumar B.;  Lang J.;  Lehman N.L.;  Mandt R.;  Nguyen P.;  Pilarski R.;  Rai K.;  Schoenfield L.;  Senecal K.;  Wakely P.;  Hansen P.;  Lechan R.;  Powers J.;  Tischler A.;  Grizzle W.E.;  Sexton K.C.;  Kastl A.;  Henderson J.;  Porten S.;  Waldmann J.;  Fassnacht M.;  Asa S.L.;  Schadendorf D.;  Couce M.;  Graefen M.;  Huland H.;  Sauter G.;  Schlomm T.;  Simon R.;  Tennstedt P.;  Olabode O.;  Nelson M.;  Bathe O.;  Carroll P.R.;  Chan J.M.;  Disaia P.;  Glenn P.;  Kelley R.K.;  Landen C.N.;  Phillips J.;  Prados M.;  Simko J.;  Smith-McCune K.;  VandenBerg S.;  Roggin K.;  Fehrenbach A.;  Kendler A.;  Sifri S.;  Steele R.;  Jimeno A.;  Carey F.;  Forgie I.;  Mannelli M.;  Carney M.;  Hernandez B.;  Campos B.;  Herold-Mende C.;  Jungk C.;  Unterberg A.;  von Deimling A.;  Bossler A.;  Galbraith J.;  Jacobus L.;  Knudson M.;  Knutson T.;  Ma D.;  Milhem M.;  Sigmund R.;  Godwin A.K.;  Madan R.;  Rosenthal H.G.;  Adebamowo C.;  Adebamowo S.N.;  Boussioutas A.;  Beer D.;  Giordano T.;  Mes-Masson A.-M.;  Saad F.;  Bocklage T.;  Landrum L.;  Mannel R.;  Moore K.;  Moxley K.;  Postier R.;  Walker J.;  Zuna R.;  Feldman M.;  Valdivieso F.;  Dhir R.;  Luketich J.;  Pinero E.M.M.;  Quintero-Aguilo M.;  Carlotti C.G.;  Dos Santos J.S.;  Kemp R.;  Sankarankuty A.;  Tirapelli D.;  Catto J.;  Agnew K.;  Swisher E.;  Creaney J.;  Robinson B.;  Shelley C.S.;  Godwin E.M.;  Kendall S.;  Shipman C.;  Bradford C.;  Carey T.;  Haddad A.;  Moyer J.;  Peterson L.;  Prince M.;  Rozek L.;  Wolf G.;  Bowman R.;  Fong K.M.;  Yang I.;  Korst R.;  Rathmell W.K.;  Fantacone-Campbell J.L.;  Hooke J.A.;  Kovatich A.J.;  Shriver C.D.;  DiPersio J.;  Drake B.;  Govindan R.;  Heath S.;  Ley T.;  Van Tine B.;  Westervelt P.;  Rubin M.A.;  Lee J.I.;  Aredes N.D.;  Mariamidze A.;  Van Allen E.M.;  Cherniack A.D.;  Ciriello G.;  Sander C.;  Schultz N.
Favorite | View/Download：30/0 | TC[WOS]:322 TC[Scopus]:493 | Submit date：2019/01/16
cancer genome atlas  cancer genomics  combination therapy  pan-cancer  PanCanAtlas  precision oncology  signaling pathways  TCGA  therapeutics  whole exome sequencing  
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-beta-Smad signaling pathway Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 341,Page: 38-50
Authors:  Zhou, Fayang;  Wang, Anqi;  Li, Dan;  Wang, Yitao;  Lin, Ligen
View | Adobe PDF | Favorite | View/Download：531/22 | TC[WOS]:12 TC[Scopus]:16 | Submit date：2018/10/30
Liver Fibrosis  Hepatic Stellate Cells  Penthorum Chinense Pursh  Pinocembrin  Sma- And Mad-related Proteins  Silent Mating Type Information Regulation 2 Homolog 3  
Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formation After Bone Marrow Ablation Journal article
JOURNAL OF BONE AND MINERAL RESEARCH, 2017,Volume: 32,Issue: 11,Page: 2194-2206
Authors:  Xu, Wei;  Luo, Fengtao;  Wang, Quan;  Tan, Qiaoyan;  Huang, Junlan;  Zhou, Siru;  Wang, Zuqiang;  Sun, Xianding;  Kuang, Liang;  Jin, Min;  Su, Nan;  Jiang, Wanling;  Chen, Liang;  Qi, Huabing;  Zhu, Ying;  Chen, Bo;  Chen, Hangang;  Chen, Shuai;  Gao, Yu;  Xu, Xiaoling;  Deng, Chuxia;  Chen, Lin;  Xie, Yangli;  Du, Xiaolan
Favorite | View/Download：40/0 | TC[WOS]:3 TC[Scopus]:6 | Submit date：2018/10/30
Bone Marrow Ablation  Fgfr2  Bone Formation  Wnt/beta-catenin  
Potential therapeutic targets of triple-negative breast cancer based on its intrinsic subtype Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 42,Page: 73329-73344
Authors:  Shao, Fangyuan;  Sun, Heng;  Deng, Chu-Xia
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Cancer Therapy  Tnbc Subtype  Cscs  Drug Resistance  Cancer Targets  
DAPK1 as an independent prognostic marker in liver cancer Journal article
PEERJ, 2017,Volume: 5
Authors:  Li, Ling;  Guo, Libin;  Wang, Qingshui;  Liu, Xiaolong;  Zeng, Yongyi;  Wen, Qing;  Zhang, Shudong;  Kwok, Hang Fai;  Lin, Yao;  Liu, Jingfeng
Favorite | View/Download：56/0 | TC[WOS]:5 TC[Scopus]:10 | Submit date：2018/10/30
Liver Cancer  Ihc  Survival  Dapk1  Prognosis