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Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View  |  Adobe PDF(2621Kb)  |  Favorite  |  View/Download:814/37  |  Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(3226Kb)  |  Favorite  |  View/Download:559/32  |  Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Cucurbitacin B suppresses metastasis mediated by reactive oxygen species (ROS) via focal adhesion kinase (FAK) in breast cancer MDA-MB-231 cells Journal article
CHINESE JOURNAL OF NATURAL MEDICINES, 2018,Volume: 16,Issue: 1,Page: 10-19
Authors:  Luo Wei-Wei;  Zhao Wen-Wen;  Lu Jin-Jian;  Wang Yi-Tao;  Chen Xiu-Ping
Favorite  |  View/Download:25/0  |  Submit date:2018/10/30
Cucurbitacin b  Metastasis  Ros  Fak  Breast Cancer  
Garcinone E induces apoptosis and inhibits migration and invasion in ovarian cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Xu, Xiao-Huang;  Liu, Qian-Yu;  Li, Ting;  Liu, Jian-Lin;  Chen, Xin;  Huang, Li;  Qiang, Wen-An;  Chen, Xiuping;  Wang, Yitao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(5330Kb)  |  Favorite  |  View/Download:512/14  |  Submit date:2018/10/30
Cytotoxic cassane diterpenoids from the seeds of Caesalpinia sappan Journal article
CHINESE CHEMICAL LETTERS, 2017,Volume: 28,Issue: 8,Page: 1711-1715
Authors:  Wu, Zheng-Feng;  Bao, Han;  Zhou, Fa-Yang;  Liu, Jing-Xin;  Meng, Fan-Cheng;  Feng, Lu;  Lu, Jin-Jian;  Zhang, Qing-Wen;  Ye, Yang;  Lin, Li-Gen
Favorite  |  View/Download:23/0  |  Submit date:2018/10/30
Caesalpinia Sappan  Cassane Diterpenoid  Phanginin  Caesalsappanin  Cytotoxicity  
Osthole inhibited TGF beta-induced epithelial-mesenchymal transition (EMT) by suppressing NF-kappa B mediated Snail activation in lung cancer A549 cells Journal article
CELL ADHESION & MIGRATION, 2017,Volume: 11,Issue: 5-6,Page: 464-475
Authors:  Feng, Haitao;  Lu, Jin-Jian;  Wang, Yitao;  Pei, Lixia;  Chen, Xiuping
View  |  Adobe PDF(1506Kb)  |  Favorite  |  View/Download:468/13  |  Submit date:2018/10/30
Emt  Nf-kappa b  Osthole Snail  Tgf-beta 1  
2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells Journal article
Free Radical Biology and Medicine, 2016,Volume: 92,Page: 61-77
Authors:  Sun W.;  Bao J.;  Lin W.;  Gao H.;  Zhao W.;  Zhang Q.;  Leung C.-H.;  Ma D.-L.;  Lu J.;  Chen X.
Favorite  |  View/Download:12/0  |  Submit date:2018/11/06
Apoptosis  Cancer  Mam  Necroptosis  No  Ros  
Psoralidin induced reactive oxygen species (ROS)-dependent DNA damage and protective autophagy mediated by NOX4 in breast cancer cells Journal article
Phytomedicine, 2016,Volume: 23,Issue: 9,Page: 939
Authors:  Ren G.;  Luo W.;  Sun W.;  Niu Y.;  Ma D.-L.;  Leung C.-H.;  Wang Y.;  Lu J.-J.;  Chen X.
Favorite  |  View/Download:11/0  |  Submit date:2018/10/31
Autophagy  Dna Damage  Nox4  Psoralidin  Ros  
Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in MCF-7 breast cancer cells Journal article
Journal of Natural Medicines, 2015,Volume: 69,Issue: 4,Page: 522-530
Authors:  Ren G.;  Sha T.;  Guo J.;  Li W.;  Lu J.;  Chen X.
Favorite  |  View/Download:8/0  |  Submit date:2018/12/28
Autophagy  Breast Cancer  Cucurbitacin b  Dna Damage  Ros  
Isocryptotanshinone Induced Apoptosis and Activated MAPK Signaling in Human Breast Cancer MCF-7 Cells Journal article
Journal of Breast Cancer, 2015,Volume: 18,Issue: 2,Page: 112-118
Authors:  Zhang X.;  Luo W.;  Zhao W.;  Lu J.;  Chen X.
Favorite  |  View/Download:3/0  |  Submit date:2018/12/28
Apoptosis  Breast Neoplasms  Isocryptotanshinone  Mitogenactivated Protein Kinases