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BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1-MCM2 signaling during pregnancy Journal article
Human molecular genetics, 2018
Authors:  Xiaoling Xu;  Eric Chen;  Lihua Mo;  Lei Zhang;  Fangyuan Shao;  Kai Miao;  Jianlin Liu;  Sek Man Su;  Monica Valecha;  Un In Chan;  Hongping Zheng;  Mark Chen;  Weiping Chen;  Qiang Chen;  Haiqing Fu;  Mirit I. Aladjem;  Yanzhen He;  Chu-Xia Deng
Favorite  |  View/Download:38/0  |  Submit date:2018/12/17
BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition Journal article
Oncogene, 2018,Issue: 37,Page: 6341–6356
Authors:  Baoyuan Zhang;  Junfang Lyu;  Yifan Liu;  Changjie Wu;  Eun Ju Yang;  Lakhansing Pardeshi;  Kaeling Tan;  Koon Ho Wong;  Qiang Chen;  Xiaoling Xu;  Chu-Xia Deng;  Joong Sup Shim
Favorite  |  View/Download:23/0  |  Submit date:2018/12/17
BRCA1 function in the intra-S checkpoint is activated by acetylation via a pCAF/SIRT1 axis Journal article
ONCOGENE, 2018,Volume: 37,Issue: 17,Page: 2343-2350
Authors:  Lahusen, Tyler J.;  Kim, Seung-Jin;  Miao, Kai;  Huang, Zebin;  Xu, Xiaoling;  Deng, Chu-Xia
Favorite  |  View/Download:29/0  |  Submit date:2018/10/30
WEE1 inhibition targets cell cycle checkpoints for triple negative breast cancers to overcome cisplatin resistance Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Zheng, Hongping;  Shao, Fangyuan;  Martin, Scots;  Xu, Xiaoling;  Deng, Chu-Xia
Favorite  |  View/Download:19/0  |  Submit date:2018/10/30
Current Progresses of Single Cell DNA Sequencing in Breast Cancer Research Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2017,Volume: 13,Issue: 8,Page: 949-960
Authors:  Liu, Jianlin;  Adhav, Ragini;  Xu, Xiaoling
Favorite  |  View/Download:23/0  |  Submit date:2018/10/30
Cancer Stem Cells  Intratumor Heterogeneity  Intertumor Heterogeneity  Breast Cancer  Single Cell Sequencing  
Drug repurposing screen identifies lestaurtinib amplifies the ability of the poly (ADP-ribose) polymerase 1 inhibitor AG14361 to kill breast cancer associated gene-1 mutant and wild type breast cancer cells Journal article
Breast Cancer Research, 2014,Volume: 16,Issue: 3
Authors:  Vazquez-Ortiz G.;  Chisholm C.;  Xu X.;  Lahusen T.J.;  Li C.;  Sakamuru S.;  Huang R.;  Thomas C.J.;  Xia M.;  Deng C.
Favorite  |  View/Download:12/0  |  Submit date:2018/12/13