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Development of a Liposomal Formulation of Acetyltanshinone IIA for Breast Cancer Therapy Journal article
MOLECULAR PHARMACEUTICS, 2019,Volume: 16,Issue: 9,Page: 3873-3886
Authors:  Qi Wang;  Man Luo;  Na We;  Alex Chang;  Kathy Qian Luo
Favorite | View/Download:38/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/05/12
Anti-breast Cancer Drugs  Acetyltanshinone Iia (Ata)  Mpeg-liposomes  Bioavailabilit  Pharmacokinetics  Toxicity Study  
Fluidic shear stress increases the anti-cancer effects of ROS-generating drugs in circulating tumor cells Journal article
BREAST CANCER RESEARCH AND TREATMENT, 2018,Volume: 172,Issue: 2,Page: 297-312
Authors:  Regmi S;  Fung TS;  Lim S;  Luo KQ
Favorite | View/Download:18/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2018/10/30
Circulating Tumor Cells  Shear Stress  Reactive Oxygen Species  Apoptosis  Anti-cancer Drugs  Doxorubicin  
MnSOD mediates shear stress-promoted tumor cell migration and adhesion Journal article
Free Radical Biology and Medicine, 2018,Volume: 129,Page: 46-58
Authors:  Shijun Ma;  Afu Fu;  Sierin Lim;  Geraldine Giap Ying Chiew;  Kathy Qian Lu
Favorite | View/Download:21/0 | TC[WOS]:5 TC[Scopus]:0 | Submit date:2019/01/04
Shear Stress  Tumor Cell Adhesion  Tumor Cell Migration  Reactive Oxygen Species  Mnsod  Fak  
Hemodynamic shear stress stimulates migration and extravasation of tumor cells by elevating cellular oxidative level Journal article
CANCER LETTERS, 2017,Volume: 388,Page: 239-248
Authors:  Ma, Shijun;  Fu, Afu;  Chiew, Geraldine Giap Ying;  Luo, Kathy Qian
Favorite | View/Download:27/0 | TC[WOS]:15 TC[Scopus]:0 | Submit date:2018/10/30
Circulating Tumor Cells  Shear Stress  Reactive Oxygen Species  Erk1/2  Cell Migration  Extravasation  
High Shear Stresses under Exercise Condition Destroy Circulating Tumor Cells in a Microfluidic System Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Regmi, Sagar;  Fu, Afu;  Luo, Kathy Qian
Favorite | View/Download:19/0 | TC[WOS]:42 TC[Scopus]:0 | Submit date:2018/10/30
Enhancement of the bioavailability of a novel anticancer compound (acetyltanshinone IIA) by encapsulation within mPEG-PLGA nanoparticles: A study of formulation optimization, toxicity, and pharmacokinetics Journal article
Oncotarget, 2017,Volume: 8,Issue: 7,Page: 12013-12030
Authors:  Wang Q.;  Wei N.;  Liu X.;  Chang A.;  Luo K.Q.
Favorite | View/Download:6/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2018/12/18
Acetyltanshinone Iia  Anticancer Drugs  Bioavailability  Mpeg-plga  Pharmacokinetics  Toxicity  
High expression of MnSOD promotes survival of circulating breast cancer cells and increases their resistance to doxorubicin Journal article
Oncotarget, 2016,Volume: 7,Issue: 31,Page: 50239-50257
Authors:  Fu A.;  Ma S.;  Wei N.;  Tan B.X.X.;  Tan E.Y.;  Luo K.Q.
Favorite | View/Download:7/0 | TC[WOS]:20 TC[Scopus]:0 | Submit date:2018/12/18
Apoptosis  Breast Cancer Metastasis  Circulating Tumor Cells  Doxorubicin Resistance  Mnsod  
Application of a fluorescence resonance energy transfer (FRET)-based biosensor for detection of drug-induced apoptosis in a 3D breast tumor model Journal article
Biotechnology and Bioengineering, 2015,Volume: 112,Issue: 8,Page: 1673-1682
Authors:  Anand P.;  Fu A.;  Teoh S.H.;  Luo K.Q.
Favorite | View/Download:5/0 | TC[WOS]:14 TC[Scopus]:0 | Submit date:2018/12/18
3d Breast Tumor Model  Anti-cancer Drugs  Biosensor  Fluorescence Resonance Energy Transfer (Fret)  Real-time Detection Of Apoptosis  
Characterization of proapoptotic compounds from the bark of Garcinia oblongifolia Journal article
Journal of Natural Products, 2014,Volume: 77,Issue: 5,Page: 1111-1116
Authors:  Feng C.;  Huang S.-X.;  Gao X.-M.;  Xu H.-X.;  Luo K.Q.
Favorite | View/Download:5/0 | TC[WOS]:12 TC[Scopus]:0 | Submit date:2018/12/18
A novel anti-cancer agent, acetyltanshinone IIA, inhibits oestrogen receptor positive breast cancer cell growth by down-regulating the oestrogen receptor Journal article
Cancer Letters, 2014,Volume: 346,Issue: 1,Page: 94-103
Authors:  Yu T.;  Zhou Z.;  Mu Y.;  De Lima Lopes G.;  Luo K.Q.
Favorite | View/Download:3/0 | TC[WOS]:20 TC[Scopus]:0 | Submit date:2018/12/18
Acetyltanshinone Iia  Anti-breast Cancer Agent  Fulvestrant  Oestrogen Receptor  Tamoxifen