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A novel agent attenuates cardiotoxicity and improves antitumor activity of doxorubicin in breast cancer cells Journal article
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019,Volume: 120,Issue: 4,Page: 5913-5922
Authors:  Ying Zhang;  Hongkuan Deng;  Hefeng Zhou;  Yucong Lu;  Luchen Shan;  Simon Ming‐Yuen Lee;  Guozhen Cui
Favorite | View/Download:242/0 | TC[WOS]:6 TC[Scopus]:0 | Submit date:2020/01/16
Antitumor  Biotin-conjugated Adtm Analog (Baa)  Cardioprotection  Cardiotoxicity  Doxorubicin (Dox)  
pH-Responsive prodrug nanoparticles based on a sodium alginate derivative for selective co-release of doxorubicin and curcumin into tumor cells Journal article
NANOSCALE, 2017,Volume: 9,Issue: 34,Page: 12533-12542
Authors:  Gao, Cheng;  Tang, Fan;  Gong, Guiyi;  Zhang, Jianxiang;  Hoi, Maggie P. M.;  Lee, Simon M. Y.;  Wang, Ruibing
Favorite | View/Download:18/0 | TC[WOS]:44 TC[Scopus]:0 | Submit date:2018/10/30
A novel agent enhances the chemotherapeutic efficacy of doxorubicin in MCF-7 breast cancer cells Journal article
Frontiers in Pharmacology, 2016,Volume: 7,Issue: AUG
Authors:  Wang L.;  Chan J.Y.;  Zhou X.;  Cui G.;  Yan Z.;  Wang L.;  Yan R.;  Di L.;  Wang Y.;  Hoi M.P.;  Shan L.;  Lee S.M.
Favorite | View/Download:12/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2018/11/06
Breast Cancer  Danshensu  Doxorubicin  Glycolysis  Grp78 Protein  Tetramethylpyrazine  
A novel agent exerts antitumor activity in breast cancer cells by targeting mitochondrial complex II Journal article
Oncotarget, 2016,Volume: 7,Issue: 22,Page: 32054-32064
Authors:  Wang L.;  Zhang X.;  Cui G.;  Chan J.Y.-W.;  Wang L.;  Li L.;  Shan L.;  Xu C.;  Zhang Q.;  Wang Y.;  Di L.;  Lee S.M.-Y.
Favorite | View/Download:9/0 | TC[WOS]:20 TC[Scopus]:0 | Submit date:2018/11/06
Breast Cancer  Danshensu  Mitochondrial Complex Ii  Reactive Oxygen Species  Tetramethylpyrazine  
A Novel Danshensu Derivative Prevents Cardiac Dysfunction and Improves the Chemotherapeutic Efficacy of Doxorubicin in Breast Cancer Cells Journal article
Journal of Cellular Biochemistry, 2016,Volume: 117,Issue: 1,Page: 94-105
Authors:  Liang Wang;  Xiaojing Zhang;  Judy Yuet‐Wa Chan;  Luchen Shan;  Guozhen Cui;  Qingbin Cui;  Yingfei Wang;  Jingjing Li;  Huanxian Chen;  Qingwen Zhang;  Pei Yu;  Yifan Han;  Yuqiang Wang;  Simon Ming‐Yuen Lee
Favorite | View/Download:11/0 | TC[WOS]:17 TC[Scopus]:0 | Submit date:2018/11/06
Breast Cancer  Cardiotoxicity  Doxorubicin  Mitochondrial Biogenesis  
Rhodamine B-conjugated encrypted vipericidin nonapeptide is a potent toxin to zebrafish and associated with in vitro cytotoxicity Journal article
Biochimica et Biophysica Acta - General Subjects, 2015,Volume: 1850,Issue: 6,Page: 1253-1260
Authors:  Liang Wang;  Judy Y.W. Chan;  Juciane V. Rêgo;  Cheong-Meng Chong;  Nana Ai;  Cláudio B. Falcão;  Gandhi Rádis-Baptista;  Simon M.Y. Lee
Favorite | View/Download:12/0 | TC[WOS]:14 TC[Scopus]:0 | Submit date:2018/11/06
Cell-penetrating Peptide  Cytotoxin  Encrypted Peptides  Rhodamine B-conjugated Peptide  Vipericidins  Zebra-fish Model  
Discovery of Rho-kinase inhibitors by docking-based virtual screening Journal article
Molecular BioSystems, 2013,Volume: 9,Issue: 6,Page: 1511
Authors:  Shen M.;  Yu H.;  Li Y.;  Li P.;  Pan P.;  Zhou S.;  Zhang L.;  Li S.;  Lee S.M.-Y.;  Hou T.
Favorite | View/Download:11/0 | TC[WOS]:43 TC[Scopus]:0 | Submit date:2018/10/30
Bisdemethoxycurcumin suppresses MCF-7 cells proliferation by inducing ROS accumulation and modulating senescence-related pathways Journal article
Pharmacological Reports, 2013,Volume: 65,Issue: 3,Page: 700
Authors:  Ying-Bo Li;  Jian-Li Gao;  Zhang-Feng Zhong;  Pui-Man Hoi;  Simon Ming-Yuen Lee;  Yi-Tao Wang
Favorite | View/Download:13/0 | TC[WOS]:29 TC[Scopus]:0 | Submit date:2018/10/30
Bisdemethoxycurcumin (Bdmc)  Breast Cancer  Reactive Oxidative Species (Ros)  Rhizoma Curcumae Longae  
Yanhusuo extract inhibits metastasis of breast cancer cells by modulating mitogen-activated protein kinase signaling pathways Journal article
Oncology Reports, 2008,Volume: 20,Issue: 4,Page: 819
Authors:  Gao J.-L.;  Shi J.-M.;  He K.;  Zhang Q.-W.;  Li S.-P.;  Lee S.M.-Y.;  Wang Y.-T.
Favorite | View/Download:9/0 | TC[WOS]:29 TC[Scopus]:0 | Submit date:2018/10/30
Breast Cancer  Cell Invasion  Corydalis Yanhusuo  Metalloproteinases  Mitogen-activated Protein Kinase  
Activation of iberiotoxin-sensitive, Ca 2+-activated K + channels of porcine isolated left anterior descending coronary artery by diosgenin Journal article
European Journal of Pharmacology, 2004,Volume: 502,Issue: 1-2,Page: 123-133
Authors:  Au A.L.S.;  Kwok C.C.;  Lee A.T.C.;  Kwan Y.W.;  Lee M.M.S.;  Zhang R.-Z.;  Ngai S.M.;  Lee S.M.Y.;  He G.-W.;  Fung K.P.
Favorite | View/Download:13/0 | TC[WOS]:39 TC[Scopus]:0 | Submit date:2018/11/06
Ca 2+-activated k + (Bk Ca) Channel  Diosgenin  Iberiotoxin-sensitive  Oestrogen Receptor  Porcine Coronary Artery