UM
(Note: the search results are based on claimed items)

Browse/Search Results:  1-5 of 5 Help

Filters        
Selected(0)Clear Items/Page:    Sort:
Anticancer effects of some novel dichloroacetophenones through the inhibition of pyruvate dehydrogenase kinase 1 Journal article
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2018,Volume: 123,Page: 43-55
Authors:  Zhang, Shao-Lin;  Yang, Zheng;  Hu, Xiaohui;  Chakravarty, Harapriya;  Tam, Kin Yip
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Dichloroacetophenone  Pyruvate Dehydrogenase Kinase  Pyruvate Dehydrogenase Complex  Anticancer Activity  Metabolic Reprogramming  
Phenyl butyrate inhibits pyruvate dehydrogenase kinase 1 and contributes to its anti-cancer effect Conference paper
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, Zhuhai, PEOPLES R CHINA, 2016-8-23-26
Authors:  Zhang, Wen;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
Favorite  |  View/Download:8/0  |  Submit date:2018/10/30
Phenyl Butyrate  Cancer  Pyruvate Dehydrogenase  Pyruvate Dehydrogenase Kinase 1  Tumor Metabolism  
Geniposide improves insulin production and reduces apoptosis in high glucose-induced glucotoxic insulinoma cells Journal article
European Journal of Pharmaceutical Sciences, 2017,Volume: 110,Page: 70-76
Authors:  Guo L.X.;  Liu J.H.;  Zheng X.X.;  Yin Z.Y.;  Kosaraju J.;  Tam K.Y.
Favorite  |  View/Download:11/0  |  Submit date:2018/12/18
Apoptosis  Geniposide  Glucose-stimulated Insulin Secretion  Glucotoxicity  
Pharmacological synergism of 2,2-dichloroacetophenone and EGFR-TKi to overcome TKi-induced resistance in NSCLC cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2017,Volume: 815,Page: 80-87
Authors:  Yang, Zheng;  Hu, Xiaohui;  Zhang, Shaolin;  Zhang, Wen;  Tam, Kin Yip
Favorite  |  View/Download:19/0  |  Submit date:2018/10/30
Synergism  Dichloroacetophenone  Dichloroacetate  Egfr  Apoptosis  Acquired Resistance  
Anti-cancer synergy of dichloroacetate and EGFR tyrosine kinase inhibitors in NSCLC cell lines Journal article
European Journal of Pharmacology, 2016,Volume: 789,Page: 458-467
Authors:  Yang Z.;  Tam K.Y.
Favorite  |  View/Download:3/0  |  Submit date:2018/12/18
Dichloroacetate  Drug Combination  Epidermal Growth Factor Receptor  Erlotinib  Gefitinib  Pyruvate Dehydrogenase Kinase