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IGF-1-Mediated Survival from Induced Death of Human Primary Cultured Retinal Pigment Epithelial Cells Is Mediated by an Akt-Dependent Signaling Pathway Journal article
MOLECULAR NEUROBIOLOGY, 2018,Volume: 55,Issue: 3,Page: 1915-1927
Authors:  Zheng, Wenhua;  Meng, Qian;  Wang, Haitao;  Yan, Fengxia;  Little, Peter J.;  Deng, Xinguo;  Lin, Shaofen
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
Retinopathy  Serum Deprivation  Cell Signaling  Apoptosis  Growth Factors  
Insulin-like growth factor-1 activates PI3K/Akt signalling to protect human retinal pigment epithelial cells from amiodarone-induced oxidative injury Journal article
BRITISH JOURNAL OF PHARMACOLOGY, 2018,Volume: 175,Issue: 1,Page: 125-139
Authors:  Liao, Rifang;  Yan, Fengxia;  Zeng, Zhuanping;  Wang, Haitao;  Qiu, Kaifeng;  Xu, Jinying;  Zheng, Wenhua
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Amiodarone-Induced Retinal Neuronal Cell Apoptosis Attenuated by IGF-1 via Counter Regulation of the PI3k/Akt/FoxO3a Pathway Journal article
MOLECULAR NEUROBIOLOGY, 2017,Volume: 54,Issue: 9,Page: 6931-6943
Authors:  Liao, Rifang;  Yan, Fengxia;  Zeng, Zhuanping;  Farhan, Mohd;  Little, Peter;  Quirion, Remi;  Srivastava, Lalit K.;  Zheng, Wenhua
Favorite  |  View/Download:10/0  |  Submit date:2018/10/30
Amiodarone  Foxo3a  Akt  Antiarrhythmic  Apoptosis  Neuroprotection  
Artemisinin Protects Retinal Neuronal Cells against Oxidative Stress and Restores Rat Retinal Physiological Function from Light Exposed Damage Journal article
ACS Chemical Neuroscience, 2017,Volume: 8,Issue: 8,Page: 1713-1723
Authors:  Yan F.;  Wang H.;  Gao Y.;  Xu J.;  Zheng W.
Favorite  |  View/Download:3/0  |  Submit date:2018/12/21
AMD  artemisin  ERK1/2  H2O2  p38  ROS  
Artemisinin protects PC12 cells against β-amyloid-induced apoptosis through activation of the ERK1/2 signaling pathway Journal article
Redox Biology, 2017,Volume: 12,Page: 625-633
Authors:  Zeng Z.;  Xu J.;  Zheng W.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/21
Alzheimer's Disease  Artemisinin  Aβ25–35  Erk1/2  Pc12 Cells  
The Atypical Antipsychotic Agent, Clozapine, Protects Against Corticosterone-Induced Death of PC12 Cells by Regulating the Akt/FoxO3a Signaling Pathway Journal article
MOLECULAR NEUROBIOLOGY, 2017,Volume: 54,Issue: 5,Page: 3395-3406
Authors:  Zeng, Zhiwen;  Wang, Xue;  Bhardwaj, Sanjeev K.;  Zhou, Xuanhe;  Little, Peter J.;  Quirion, Remi;  Srivastava, Lalit K.;  Zheng, Wenhua
Favorite  |  View/Download:11/0  |  Submit date:2018/10/30
Schizophrenia  Clozapine  Corticosterone  Pi3k/akt/foxo3a  Neuroprotection  
Lithium ions attenuate serum-deprivation-induced apoptosis in PC12 cells through regulation of the Akt/FoxO1 signaling pathways Journal article
Psychopharmacology, 2016,Volume: 233,Issue: 5,Page: 785
Authors:  Zeng Z.;  Wang H.;  Shang F.;  Zhou L.;  Little P.J.;  Quirion R.;  Zheng W.
Favorite  |  View/Download:4/0  |  Submit date:2018/10/30
Apoptosis  Lithium  Neuroprotection  Pi3k/akt/foxo1  Serum Deprivation  
Insulin-like growth factor-1-induced phosphorylation of transcription factor FKHRL1 is mediated by phosphatidylinositol 3-kinase/Akt kinase and role of this pathway in insulin-like growth factor-1-induced survival of cultured hippocampal neurons Journal article
Molecular Pharmacology, 2002,Volume: 62,Issue: 2,Page: 225-233
Authors:  Zheng W.-H.;  Kar S.;  Quirion R.
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Insulin-like growth factor-1-induced phosphorylation of the Forkhead family transcription factor FKHRL1 is mediated by Akt kinase in PC12 cells Journal article
Journal of Biological Chemistry, 2000,Volume: 275,Issue: 50,Page: 39152-39158
Authors:  Zheng W.-H.;  Kar S.;  Quirion R.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/21