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Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
View  |  Adobe PDF(2009Kb)  |  Favorite  |  View/Download:309/46  |  Submit date:2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Ponatinib exerts anti-angiogenic effects in the zebrafish and human umbilical vein endothelial cells via blocking VEGFR signaling pathway Journal article
Oncotarget, 2018,Volume: 9,Issue: 62,Page: 31958-31970
Authors:  Nana Ai;  Cheong-Meng Chong.;  Weiting Chen;  Zhe Hu;  Huanxing Su;  Guokai Chen;  Queenie Wing Lei Wong;  Wei Ge
Favorite  |  View/Download:7/0  |  Submit date:2018/12/11
Angiogenesis  Enos  Huvec  Mapk  Ponatinib  
Discovery and preliminary SAR of 14-aryloxy-andrographolide derivatives as antibacterial agents with immunosuppressant activity Journal article
RSC ADVANCES, 2018,Volume: 8,Issue: 17,Page: 9440-9456
Authors:  Li, Feng;  Li, Xiao-Min;  Sheng, Dekuan;  Chen, Shao-Ru;  Nie, Xin;  Liu, Zhuyun;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Wang, Ying;  Zhou, Guo-Chun
View  |  Adobe PDF(583Kb)  |  Favorite  |  View/Download:132/9  |  Submit date:2018/10/30
Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth Journal article
CANCER LETTERS, 2017,Volume: 409,Page: 91-103
Authors:  Lyu, Junfang;  Yang, Eun Ju;  Head, Sarah A.;  Ai, Nana;  Zhang, Baoyuan;  Wu, Changjie;  Li, Ruo-Jing;  Liu, Yifan;  Yang, Chen;  Dang, Yongjun;  Kwon, Ho Jeong;  Ge, Wei;  Liu, Jun O.;  Shim, Joong Sup
Favorite  |  View/Download:13/0  |  Submit date:2018/10/30
Cholesterol Trafficking  Angiogenesis  Tumor  Lysosome  Cepharanthine  
Venom-based peptide therapy: insights into anti-cancer mechanism Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 59,Page: 100908-100930
Authors:  Ma, Rui;  Mahadevappa, Ravikiran;  Kwok, Hang Fai
Favorite  |  View/Download:13/0  |  Submit date:2018/10/30
Anticancer Mechanism  Venom  Metastasis  Targeted Therapy  Signaling Pathway  
Modulating the phenotype of host macrophages to enhance osteogenesis in MSC-laden hydrogels: Design of a glucomannan coating material Journal article
BIOMATERIALS, 2017,Volume: 139,Page: 39-55
Authors:  Niu, Yiming;  Li, Qiu;  Xie, Ruiyu;  Liu, Shang;  Wang, Ruibing;  Xing, Panfei;  Shi, Yuchen;  Wang, Yitao;  Dong, Lei;  Wang, Chunming
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Bioactive Coating  Glucomannan Polysaccharides  Scaffold-tissue Integration  Macrophages  Osteogenesis  
Bioengineered three-dimensional co-culture of cancer cells and endothelial cells: A model system for dual analysis of tumor growth and angiogenesis Journal article
BIOTECHNOLOGY AND BIOENGINEERING, 2017,Volume: 114,Issue: 8,Page: 1865-1877
Authors:  Chiew, Geraldine Giap Ying;  Wei, Na;  Sultania, Samiksha;  Lim, Sierin;  Luo, Kathy Qian
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3d Co-culture  Angiogenesis  Liver Cancer  Endothelial Cells  Fret  Tumor Growth  
Phytochemicals - A Novel and Prominent Source of Anti-cancer Drugs Against Colorectal Cancer Journal article
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2017,Volume: 20,Issue: 5,Page: 376-394
Authors:  Mahadevappa, Ravikiran;  Kwok, Hang Fai
Favorite  |  View/Download:8/0  |  Submit date:2018/10/30
Colorectal Cancer  Phytochemicals  Anti-cancer  Anti-oxidants  Curcumin  Resveratrol  Withaferin a  
Enhancement of the bioavailability of a novel anticancer compound (acetyltanshinone IIA) by encapsulation within mPEG-PLGA nanoparticles: A study of formulation optimization, toxicity, and pharmacokinetics Journal article
Oncotarget, 2017,Volume: 8,Issue: 7,Page: 12013-12030
Authors:  Wang Q.;  Wei N.;  Liu X.;  Chang A.;  Luo K.Q.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/18
Acetyltanshinone Iia  Anticancer Drugs  Bioavailability  Mpeg-plga  Pharmacokinetics  Toxicity  
Application of a fluorescence resonance energy transfer (FRET)-based biosensor for detection of drug-induced apoptosis in a 3D breast tumor model Journal article
Biotechnology and Bioengineering, 2015,Volume: 112,Issue: 8,Page: 1673-1682
Authors:  Anand P.;  Fu A.;  Teoh S.H.;  Luo K.Q.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/18
3d Breast Tumor Model  Anti-cancer Drugs  Biosensor  Fluorescence Resonance Energy Transfer (Fret)  Real-time Detection Of Apoptosis