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Inhibition of lung cancer by 2-methoxy-6-acetyl-7-methyljuglone (MAM) through induction of necroptosis by targeting receptor-interacting protein 1 (RIP1) Journal article
Antioxidants & Redox Signaling, 2018,Volume: 0,Issue: JA
Authors:  Sun W;  Yu J;  Gao H;  Wu X;  Wang S;  Hou Y;  Lu JJ;  Chen X
Favorite  |  View/Download:13/0  |  Submit date:2019/01/16
MLKL mediates apoptosis via a mutual regulation with PERK/eIF2α pathway in response to reactive oxygen species generation Journal article
Apoptosis, 2018,Volume: 23,Issue: 9-10,Page: 521-531
Authors:  Cao W.-X.;  Li T.;  Tang Z.-H.;  Zhang L.-L.;  Wang Z.-Y.;  Guo X.;  Su M.-X.;  Chen X.;  Lu J.-J.
Favorite  |  View/Download:12/0  |  Submit date:2018/12/28
Apoptosis  Chelerythrine  Eif2α  Mlkl  Ros  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View  |  Adobe PDF(2621Kb)  |  Favorite  |  View/Download:814/37  |  Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
A novel design of a polynuclear co-delivery system for safe and efficient cancer therapy Journal article
CHEMICAL COMMUNICATIONS, 2018,Volume: 54,Issue: 63,Page: 8737-8740
Authors:  Xing, Lei;  Zhang, Jia-Liang;  Zhou, Tian-Jiao;  He, Yu-Jing;  Cui, Peng-Fei;  Gong, Jia-Hui;  Sun, Minjie;  Lu, Jin-Jian;  Huang, Zhangjian;  Jin, Liang;  Jiang, Hu-Lin
Favorite  |  View/Download:29/0  |  Submit date:2018/10/30
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(3226Kb)  |  Favorite  |  View/Download:560/32  |  Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Diethyl blechnic, a novel natural product isolated from salvia miltiorrhiza bunge, inhibits doxorubicin-induced apoptosis by inhibiting ROS and activating JNK1/2 Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 6
Authors:  Yu J.;  Gao H.;  Wu C.;  Xu Q.-M.;  Lu J.-J.;  Chen X.
Favorite  |  View/Download:8/0  |  Submit date:2018/12/28
Cardiotoxicity  Diethyl Blechnic  Dox  Jnk1/2  Ros  
Baicalein protects tert-butyl hydroperoxide-induced hepatotoxicity dependent of reactive oxygen species removal Journal article
MOLECULAR MEDICINE REPORTS, 2017,Volume: 16,Issue: 6,Page: 8392-8398
Authors:  Wang, Ya-Fang;  Tang, Zheng-Hai;  Li, Ting;  Xu, Xiao-Huang;  Chen, Xiuping;  Wang, Ying;  Wang, Yi-Tao;  Lu, Jin-Jian
Favorite  |  View/Download:26/0  |  Submit date:2018/10/30
Baicalein  Liver Protection  Reactive Oxygen Species  Apoptosis  
Garcinone E induces apoptosis and inhibits migration and invasion in ovarian cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Xu, Xiao-Huang;  Liu, Qian-Yu;  Li, Ting;  Liu, Jian-Lin;  Chen, Xin;  Huang, Li;  Qiang, Wen-An;  Chen, Xiuping;  Wang, Yitao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(5330Kb)  |  Favorite  |  View/Download:512/14  |  Submit date:2018/10/30
Natural products to prevent drug resistance in cancer chemotherapy: a review Journal article
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 2017,Volume: 1401,Issue: 1,Page: 19-27
Authors:  Yuan, Renyikun;  Hou, Ying;  Sun, Wen;  Yu, Jie;  Liu, Xin;  Niu, Yanan;  Lu, Jin-Jian;  Chen, Xiuping
Favorite  |  View/Download:22/0  |  Submit date:2018/10/30
Drug Resistance  Cancer  Natural Products  Nonapoptotic Cell Death  
Induction of reactive oxygen species-stimulated distinctive autophagy by chelerythrine in non-small cell lung cancer cells Journal article
REDOX BIOLOGY, 2017,Volume: 12,Page: 367-376
Authors:  Tang, Zheng-Hai;  Cao, Wen-Xiang;  Wang, Zhao-Yu;  Lu, Jia-Hong;  Liu, Bo;  Chen, Xiuping;  Lu, Jin-Jian
Favorite  |  View/Download:24/0  |  Submit date:2018/10/30
Chelerythrine  Autophagy  Apoptosis  Ros  Nsclc