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Zebrafish: A Visual Model to Evaluate the Biofate of Transferrin Receptor-Targeted 7Peptide-Decorated Coumarin 6 Micelles Journal article
ACS Applied Materials and Interfaces, 2017,Volume: 9,Issue: 44,Page: 39048-39058
Authors:  Ye Li;  Xiaoning Song;  Xiang Yi;  Ruibing Wang;  Simon Ming-Yuen Lee;  Xueqing Wang;  Ying Zheng
Favorite  |  View/Download:13/0  |  Submit date:2018/11/06
7peptide  Biological Barriers  Ligand Density  Poly(Ethylene Glycol)-block-Poly(Ε-caprolactone) Micelles  Transferrin Receptor  Zebrafish  
Zebrafish: A promising in vivo model for assessing the delivery of natural products, fluorescence dyes and drugs across the blood-brain barrier Journal article
PHARMACOLOGICAL RESEARCH, 2017,Volume: 125,Page: 246-257
Authors:  Li, Ye;  Chen, Tongkai;  Miao, Xiaoqing;  Yi, Xiang;  Wang, Xueqing;  Zhao, Haitao;  Lee, Simon Ming-Yuen;  Zheng, Ying
Favorite  |  View/Download:30/0  |  Submit date:2018/10/30
Blood Brain Barrier (Bbb)  Zebrafish  Fluorescence Dyes  Natural Products  Drug Delivery Systems  Permeability  
Pluronic P85/F68 Micelles of Baicalein Could Interfere with Mitochondria to Overcome MRP2-Mediated Efflux and Offer Improved Anti-Parkinsonian Activity Journal article
Molecular Pharmaceutics, 2017,Volume: 14,Issue: 10,Page: 3331-3342
Authors:  Tongkai Chen;  Ye Li;  Chuwen Li;  Xiang Yi;  Ruibing Wang;  Simon Ming-Yuen Lee;  Ying Zheng
Favorite  |  View/Download:14/0  |  Submit date:2018/11/06
Baicalein  Fluorescence Resonance Energy Transfer (Fret)  Micelles  Mitochondria  Multidrug Resistance-associated Protein 2 (Mrp2)  Neuroprotective Effect  
Zebrafish as a visual and dynamic model to study the transport of nanosized drug delivery systems across the biological barriers Journal article
Colloids and Surfaces B: Biointerfaces, 2017,Volume: 156,Page: 227-235
Authors:  Li Y.;  Miao X.;  Chen T.;  Yi X.;  Wang R.;  Zhao H.;  Lee S.M.-Y.;  Wang X.;  Zheng Y.
Favorite  |  View/Download:12/0  |  Submit date:2018/11/06
Biological Barriers  Nanocrystals  Transport  Zebrafish  
Small-Sized mPEG PLGA Nanoparticles of Schisantherin A with Sustained Release for Enhanced Brain Uptake and Anti-Parkinsonian Activity Journal article
ACS APPLIED MATERIALS & INTERFACES, 2017,Volume: 9,Issue: 11,Page: 9516-9527
Authors:  Chen, Tongkai;  Li, Chuwen;  Li, Ye;  Yi, Xiang;  Wang, Ruibing;  Lee, Simon Ming-Yuen;  Zheng, Ying
Favorite  |  View/Download:30/0  |  Submit date:2018/10/30
Brain Delivery  Cellular Uptake  Fluorescence Resonance Energy Transfer (Fret)  Mpeg-plga Nanoparticles  Oral Bioavailability  Schisantherin a  
Oral delivery of a nanocrystal formulation of schisantherin a with improved bioavailability and brain delivery for the treatment of Parkinson's disease Journal article
Molecular Pharmaceutics, 2016,Volume: 13,Issue: 11,Page: 3864-3875
Authors:  Tongkai Chen;  Chuwen Li;  Ye Li;  Xiang Yi;  Simon Ming-Yuen Lee;  Ying Zheng
Favorite  |  View/Download:9/0  |  Submit date:2018/11/06
Brain Delivery  Dissolution  Nanocrystals  Oral Bioavailability  Parkinson's Disease (Pd)  
Transport Mechanism of Coumarin 6 Nanocrystals with Two Particle Sizes in MDCKII Monolayer and Larval Zebrafish Journal article
ACS Applied Materials and Interfaces, 2016,Volume: 8,Issue: 20,Page: 12620-12630
Authors:  Xiaoqing Miao;  Ye Li;  Xueqing Wang;  Simon Ming-Yuen Lee;  Ying Zheng
Favorite  |  View/Download:7/0  |  Submit date:2018/11/06
Epithelial Cells  Nanocrystals  Particle Size  Transport Mechanism  Zebrafish  
Zebrafish: An in-vivo model to evaluate absorption and biodistribution of nanocrystals Journal article
Nanomedicine: Nanotechnology, Biology, and Medicine, 2016,Volume: 12,Issue: 2,Page: 573
Authors:  Ye Li;  Xiaoqing Miao;  Liang Wang;  Xiang Yi;  Simon M.Y. Lee;  Ying Zheng
Favorite  |  View/Download:5/0  |  Submit date:2020/04/08
Enhanced in vitro and in vivo uptake of a hydrophobic model drug coumarin-6 in the presence of cucurbit[7]uril Journal article
MedChemComm, 2015,Volume: 6,Issue: 7,Page: 1370-1374
Authors:  Xiaoqing Miao;  Ye Li;  Ian Wyman;  Simon M. Y. Lee;  Donal H. Macartney;  Ying Zheng;  Ruibing Wang
Favorite  |  View/Download:13/0  |  Submit date:2018/11/06
Nanosuspension Development of scutellarein as an active and rapid orally absorbed precursor of its BCS class IV glycoside scutellarin Journal article
Journal of Pharmaceutical Sciences, 2014,Volume: 103,Issue: 11,Page: 3576-3584
Authors:  Yang X.;  Miao X.;  Cao F.;  Li S.;  Ai N.;  Chang Q.I.;  Lee S.M.Y.;  Zheng Y.
Favorite  |  View/Download:13/0  |  Submit date:2018/11/06
Absorption  Cerebral Hemorrhage  Metabolism  Nanotechnology  Oral Drug Delivery  Precursor  Scutellarin (Sg)  Solubility  Zebrafish