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Discovery, synthesis, and functional characterization of a novel neuroprotective natural product from the fruit of alpinia oxyphylla for use in Parkinson's disease through LC/MS-based multivariate data analysis-guided fractionation Journal article
Journal of Proteome Research, 2016,Volume: 15,Issue: 8,Page: 2595-2606
Authors:  Guohui Li;  Zaijun Zhang;  Quan Quan;  Renwang Jiang;  Samuel S.W. Szeto;  Shuai Yuan;  Wing-tak Wong;  Herman H. C. Lam;  Simon Ming-Yuen Lee;  Ivan K. Chu
Favorite  |  View/Download:8/0  |  Submit date:2018/11/06
Natural Products  Neuroprotective  Nrf2  Parkinson's Disease  Proteomics  
The transcriptome of the zoanthid protopalythoa variabilis (cnidaria, anthozoa) predicts a basal repertoire of toxin-like and venom-Auxiliary polypeptides Journal article
Genome Biology and Evolution, 2016,Volume: 8,Issue: 9,Page: 3045-3064
Authors:  Chen Huang;  Jean-Étienne RL Morlighem;  Hefeng Zhou;  Érica P Lima;  Paula B Gomes;  Jing Cai;  Inchio Lou;  Carlos D Pérez;  Simon Ming Lee;  Gandhi Rádis-Baptista
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Hexacorallia  Molecular Toxinology  Peptide Toxin  Rna-seq  Transcriptome  Venomics  Zoanthidea  
Anti-angiogenic activity of a new andrographolide derivative in zebrafish and HUVECs Journal article
European Journal of Pharmacology, 2016,Volume: 789,Page: 344-353
Authors:  JingjingLia;  YuranPeng;  Shang Li;  Yicheng Sun;  Judy Yuet-Wa Chan;  Guozhen Cui;  Decai Wang;  Guo-Chun Zhou;  Simon Ming-Yuen Lee
Favorite  |  View/Download:5/0  |  Submit date:2018/11/06
Andrographolide  Angiogenesis  Zebrafish  
A Novel Danshensu Derivative Prevents Cardiac Dysfunction and Improves the Chemotherapeutic Efficacy of Doxorubicin in Breast Cancer Cells Journal article
Journal of Cellular Biochemistry, 2016,Volume: 117,Issue: 1,Page: 94-105
Authors:  Liang Wang;  Xiaojing Zhang;  Judy Yuet‐Wa Chan;  Luchen Shan;  Guozhen Cui;  Qingbin Cui;  Yingfei Wang;  Jingjing Li;  Huanxian Chen;  Qingwen Zhang;  Pei Yu;  Yifan Han;  Yuqiang Wang;  Simon Ming‐Yuen Lee
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Breast Cancer  Cardiotoxicity  Doxorubicin  Mitochondrial Biogenesis  
A phosphinate-based near-infrared fluorescence probe for imaging the superoxide radical anion in vitro and in vivo Journal article
Chemical Communications, 2016,Volume: 52,Issue: 13,Page: 2679
Authors:  Jianjian Zhang;  Chuwen Li;  Rui Zhang;  Fengyuan Zhang;  Wei Liu;  Xiaoyan Liu;  Simon Ming-Yuen Lee;  Haixia Zhang
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In vivo reversal of general anesthesia by cucurbit[7]uril with zebrafish models Journal article
RSC Advances, 2015,Volume: 5,Issue: 78,Page: 63745-63752
Authors:  Huanxian Chen;  Judy Y. W. Chan;  Shengke Li;  Jessica J. Liu;  Ian W. Wyman;  Simon M. Y. Lee;  Donal H. Macartney.;  Ruibing Wang
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Study on the HPLC Chromatograms and Pro-Angiogenesis Activities of the Flowers of Panax notoginseng Journal article
Journal of Liquid Chromatography and Related Technologies, 2015,Volume: 38,Issue: 13,Page: 1286-1295
Authors:  Xie R.-F.;  Yang B.-R.;  Cheng P.-P.;  Wu S.;  Li Z.-C.;  Tang J.-Y.;  Li S.;  Tang N.;  Lee S.M.Y.;  Wang Y.-H.;  Zhou X.
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Angiogenesis  Chromatograms  Flowerof Panax Notoginseng  Zebrafish  
Rhodamine B-conjugated encrypted vipericidin nonapeptide is a potent toxin to zebrafish and associated with in vitro cytotoxicity Journal article
Biochimica et Biophysica Acta - General Subjects, 2015,Volume: 1850,Issue: 6,Page: 1253-1260
Authors:  Liang Wang;  Judy Y.W. Chan;  Juciane V. Rêgo;  Cheong-Meng Chong;  Nana Ai;  Cláudio B. Falcão;  Gandhi Rádis-Baptista;  Simon M.Y. Lee
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Cell-penetrating Peptide  Cytotoxin  Encrypted Peptides  Rhodamine B-conjugated Peptide  Vipericidins  Zebra-fish Model  
Purpurin inhibits adipocyte-derived leucine aminopeptidase and angiogenesis in a zebrafish model Journal article
Biochemical and Biophysical Research Communications, 2014,Volume: 450,Issue: 1,Page: 561-567
Authors:  Park H.;  Shim J.S.;  Kim B.S.;  Jung H.J.;  Huh T.-L.;  Kwon H.J.
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Adipocyte-derived Leucine Aminopeptidase (A-lap)  Angiogenesis  Drug Screening  Purpurin  
Protective effects of puerarin against A ß40-induced vascular dysfunction in zebrafish and human endothelial cells Journal article
European Journal of Pharmacology, 2014,Volume: 732,Issue: 1,Page: 76-85
Authors:  Lu X.-L.;  Liu J.-X.;  Wu Q.;  Long S.-M.;  Zheng M.-Y.;  Yao X.-L.;  Ren H.;  Wang Y.-G.;  Su W.-W.;  Fai Cheung R.T.;  Zeng J.-S.;  Su H.;  Pei Z.
Favorite  |  View/Download:12/0  |  Submit date:2018/12/28
Aß40  Puerarin  Vascular Protection  Zebrafish