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Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View  |  Adobe PDF(2766Kb)  |  Favorite  |  View/Download:120/5  |  Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Identification of an Iridium(III)-Based Inhibitor of Tumor Necrosis Factor-α Journal article
Journal of Medicinal Chemistry, 2016,Volume: 59,Issue: 8,Page: 4026
Authors:  Kang T.-S.;  Mao Z.;  Ng C.-T.;  Wang M.;  Wang W.;  Wang C.;  Lee S.M.-Y.;  Wang Y.;  Leung C.-H.;  Ma D.-L.
Favorite  |  View/Download:4/0  |  Submit date:2018/10/30
Combined in vivo imaging and omics approaches reveal metabolism of icaritin and its glycosides in zebrafish larvae Journal article
MOLECULAR BIOSYSTEMS, 2011,Volume: 7,Issue: 7,Page: 2128-2138
Authors:  Li, ZH (Li, Zhen Hua);  Alex, D (Alex, Deepa);  Siu, SO (Siu, Shiu On);  Chu, IK (Chu, Ivan Keung);  Renn, J (Renn, Joerg);  Winkler, C (Winkler, Christoph);  Lou, S (Lou, Shaoke);  Tsui, SKW (Tsui, Stephen Kwok-Wing);  Zhao, HY (Zhao, Hai Yu);  Yan, WR (Yan, Wendy Ru);  Mahady, GB (Mahady, Gail B.);  Li, GH (Li, Guo Hui);  Kwan, YW (Kwan, Yiu Wa);  Wang, YT (Wang, Yi Tao);  Lee, SMY (Lee, Simon Ming-Yuen)
View  |  Adobe PDF(6032Kb)  |  Favorite  |  View/Download:132/5  |  Submit date:2018/11/01
Animal-models  Flavonoids  Quercetin  Bone  Fluorescence  Absorption  Proteome  Swim  
Furanodiene induces G(2)/M cell cycle arrest and apoptosis through MAPK signaling and mitochondria-caspase pathway in human hepatocellular carcinoma cells Journal article
CANCER BIOLOGY & THERAPY, 2007,Volume: 6,Issue: 7,Page: 1044-1050
Authors:  admin;  Yang, FQ;  Li, SP;  Gao, JL;  Hu, G;  Lao, SC;  Conceicao, EL;  Fung, KP;  Wang, YT;  Lee, SMY
View  |  Adobe PDF(760Kb)  |  Favorite  |  View/Download:98/1  |  Submit date:2018/11/01
Furanodiene  Apoptosis  Hepg(2)  Caspase-3  Mitochondrial  Cytochrome c  P38  Erk