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New insights from Opisthorchis felineus genome: update on genomics of the epidemiologically important liver flukes Journal article
BMC GENOMICS, 2019
Authors:  Nikita I. Ershov;  Viatcheslav A. Mordvinov;  Egor B. Prokhortchouk;  Mariya Y. Pakharukova;  Konstantin V. Gunbin;  Kirill Ustyantsev;  Mikhail A. Genaev;  Alexander G. Blinov;  Alexander Mazur;  Eugenia Boulygina;  Svetlana Tsygankova;  Ekaterina Khrameeva;  Nikolay Chekanov;  Guangyi Fan;  An Xiao;  He Zhang;  Xun Xu;  Huanming Yang;  Victor Solovyev;  Simon Ming-Yuen Lee;  Xin Liu;  Dmitry A. Afonnikov;  Konstantin G. Skryabin
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Opisthorchiidae  Opisthorchis Felineus  Genome  Trans-splicing  Microintrons  Liver Flukes  Transcriptome  Metacercariae  
Neuroprotective Effects of BHDPC, a Novel Neuroprotectant, on Experimental Stroke by Modulating Microglia Polarization Journal article
ACS CHEMICAL NEUROSCIENCE, 2019,Volume: 10,Issue: 5,Page: 2434-2449
Authors:  Chuwen Li;  Yaqi Bian;  Yu Feng;  Fan Tang;  Liang Wang;  Maggie Pui Man Hoi;  Dan Ma;  Chao Zhao;  Simon Ming Yuen Lee
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Bhdpc  Ischemic Stroke  Microglia  Nf-κb  Creb  Pka  
Cnidarian peptide neurotoxins: a new source of various ion channel modulators or blockers against central nervous systems disease Journal article
DRUG DISCOVERY TODAY, 2019,Volume: 24,Issue: 1,Page: 189-197
Authors:  Qiwen Liao;  Yu Feng;  Binrui Yang;  Simon Ming-Yuen Lee
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Supramolecular strategy for reducing the cardiotoxicity of bedaquiline without compromising its antimycobacterial efficacy Conference paper
FOOD AND CHEMICAL TOXICOLOGY, Kunming, PEOPLES R CHINA, AUG 25-30, 2018
Authors:  Kuok, Kit Ieng;  Ng, Phoebe Choi In;  Ji, Xia;  Wang, Chunming;  Yew, Wing Wai;  Chan, Denise P. C.;  Zheng, Jun;  Lee, Simon M. Y.;  Wang, Ruibing
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Cucurbit[7]Uril  Bedaquiline  Supramolecular Formulation  Cardiotoxicity  Antimycobacterial  
Sodium tanshinone IIA sulfonate promotes endothelial integrity via regulating VE-cadherin dynamics and RhoA/ROCK-mediated cellular contractility and prevents atorvastatin-induced intracerebral hemorrhage in zebrafish Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 350,Page: 32-42
Authors:  Zhou, Zhong-Yan;  Huang, Bin;  Li, Shang;  Huang, Xiao-Hui;  Tang, Jing-Yi;  Kwan, Yiu Wa;  Hoi, Pui Man;  Lee, Simon Ming-Yuen
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Sodium Tanshinone Iia Sulfonate  Salvia Miltiorrhiza  Hemorrhagic Stroke  Atorvastatin  Rock  
Tanshinone I prevents atorvastatin-induced cerebral hemorrhage in zebrafish and stabilizes endothelial cell-cell adhesion by inhibiting. VE-cadherin internalization and actin-myosin contractility Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 128,Page: 389-398
Authors:  Huang, Bin;  Zhou, Zhong-Yan;  Li, Shang;  Huang, Xiao-Hui;  Tang, Jing-Yi;  Hoi, Maggie Pui Man;  Lee, Simon Ming Yuen
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Tanshinone I  Vascular integrity  Endothelial cell adhesion  Hemorrhagic stroke  Zebrafish  HUVECs  
Pro-angiogenic effects of Ilexsaponin A1 on human umbilical vein endothelial cells in vitro and zebrafish in vivo Journal article
PHYTOMEDICINE, 2017,Volume: 36,Page: 229-237
Authors:  Li, Jingjing;  Zhang, Jinming;  Zou, Liang;  Lee, Simon Ming-Yuen;  Yang, Cui;  Seto, Sai-Wang;  Leung, George Pak-Heng
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Ilexsaponin A1  Ilex pubescens  Pro-angiogenesis  Zebrafish  Endothelial cells  
Characterization of the Molecular Mechanisms Underlying the Chronic Phase of Stroke in a Cynomolgus Monkey Model of Induced Cerebral Ischemia Journal article
JOURNAL OF PROTEOME RESEARCH, 2017,Volume: 16,Issue: 3,Page: 1150-1166
Authors:  Law, Henry C. H.;  Szeto, Samuel S. W.;  Quan, Quan;  Zhao, Yun;  Zhang, Zaijun;  Krakovska, Olga;  Lui, Leong Ting;  Zheng, Chengyou;  Lee, Simon M. -Y.;  Siu, K. W. Michael;  Wang, Yuqiang;  Chu, Ivan K.
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stroke biology  iTRAQ  cynomolgus monkey  brain proteome  ischemia  chronic phase  
Discovery of Rho-kinase inhibitors by docking-based virtual screening Journal article
Molecular BioSystems, 2013,Volume: 9,Issue: 6,Page: 1511
Authors:  Shen M.;  Yu H.;  Li Y.;  Li P.;  Pan P.;  Zhou S.;  Zhang L.;  Li S.;  Lee S.M.-Y.;  Hou T.
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