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1. Single-cell RNA-Seq reveals cell heterogeneity and hierarchy withi.. [26]
2. BRCA1 represses DNA replication initiation through antagonizing es.. [20]
3. BRCA1 function in the intra-S checkpoint is activated by acetylati.. [18]
4. Emerging roles of SIRT1 in fatty liver diseases [16]
5. A digital microfluidic system for loop-mediated isothermal amplifi.. [15]
6. Postnatal deletion of Alk5 gene in meniscal cartilage accelerates .. [15]
7. Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formatio.. [14]
8. Epigenetic targeting drugs potentiate chemotherapeutic effects in .. [14]
9. Optimizing CRISPR/Cas9 technology for precise correction of the Fg.. [14]
10. A novel FGFR1-binding peptide attenuates the degeneration ofarticu.. [14]
11. Cyclin B1 stability is increased by interaction with BRCA1, and it.. [12]
12. Bombesin-like receptor 3 (Brs3) expression in glutamatergic, but n.. [12]
13. A novel FGFR1-binding peptide exhibits anti-tumor effect on lung c.. [12]
14. A comprehensive genomic meta-analysis identifies confirmatory role.. [12]
15. Drug screening of cancer cell lines and human primary tumors using.. [12]
16. Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenu.. [12]
17. Characterization of potential driver mutations involved in human b.. [10]
18. Centrosome amplification and a defective G2-M cell cycle checkpoin.. [10]
19. BRCA1 deficiency sensitizes breast cancer cells to bromodomain and.. [10]
20. Potential therapeutic targets of triple-negative breast cancer bas.. [9]
21. Fibroblast Growth Factor Receptor 2 Signaling in Breast Cancer [9]
22. A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations i.. [9]
23. Partial müllerian duct retention in Smad4 conditional mutant male.. [9]
24. SIRT6 Is Essential for Adipocyte Differentiation by Regulating Mit.. [8]
25. WEE1 inhibition targets cell cycle checkpoints for triple negative.. [8]
26. Generation of Smurf2 conditional knockout mice [8]
27. Analysis of Genomes and Transcriptomes of Hepatocellular Carcinoma.. [8]
28. Alcohol, stem cells and cancer [8]
29. Conditional deletion of FOXL2 and SMAD4 in gonadotropes of adult m.. [7]
30. Inhibition of Estrogen Signaling Reduces the Incidence of BRCA1-as.. [7]
31. Negative reciprocal regulation between Sirt1 and Per2 modulates th.. [7]
32. SIRT1 deacetylates TopBP1 and modulates intra-sphase checkpoint an.. [7]
33. Drug repurposing screen identifies lestaurtinib amplifies the abil.. [7]
34. A role of SMAD4 in iron metabolism through the positive regulation.. [7]
35. SMAD3 Regulates follicle-stimulating hormone synthesis by pituitar.. [6]
36. “DNA binding region“ of BRCA1 affects genetic stability through .. [6]
37. A dual-specific IGF-I/II human engineered antibody domain inhibits.. [6]
38. CRISPR-Cas9: from Genome Editing to Cancer Research [6]
39. The role of TGF-β/SMAD4 signaling in cancer [5]
40. Inhibition of AKT suppresses the initiation and progression of BRC.. [5]
41. Smad4 is required to inhibit osteoclastogenesis and maintain bone .. [5]
42. A mechanism for 1,4-Benzoquinone-induced genotoxicity [5]
43. Ammonium tetrathiomolybdate treatment targets the copper transport.. [5]
44. Tak1, Smad4 and Trim33 redundantly mediate TGF-β3 signaling durin.. [5]
45. Silencing of unsynapsed meiotic chromosomes in the mouse [5]
46. Precision Medicine for Personalized Cancer Therapy [5]
47. Fibroblast Grouth Factor Receptor (FGFR2) Mutation Related Symdrom.. [5]
48. PRAJA is overexpressed in glioblastoma and contributes to neural p.. [4]
49. Sexual Fate Change of XX Germ Cells Caused by the Deletion of SMAD.. [4]
50. Hepatic-specific disruption of SIRT6 in mice results in fatty live.. [4]
51. SIRT1 disruption in human fetal hepatocytes leads to increased acc.. [3]
52. Adapted resistance to the knockdown effect of shRNA-derived Srsf3 .. [3]
53. Induction of intrahepatic cholangiocellular carcinoma by liver-spe.. [3]

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