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Therapeutic angiogenesis after ischemic stroke: Chinese medicines, bone marrow stromal cells (bmscs) and their combinational treatment
Zhang Q.; Zhao Y.-H.
2014-02-07
Source PublicationAmerican Journal of Chinese Medicine
ISSN0192415X
Volume42Issue:1Pages:61-77
Abstract

Ischemic stroke is a clinical acute disease which causes neurological dysfunction and threatens a patient's life. Because the mechanism of pathology is complicated and most patients miss the best therapeutic window time, the effect of the treatment is not satisfied at present. Numerous studies indicated new vessels not only recuperated blood flow in the ischemic boundary zone, but also facilitated endogenous neurogenesis and improved neurological function after ischemic stroke. Therefore, angiogenesis has been an important research field in neurovascular regeneration. Recently, some Chinese medicines, bone marrow stromal cells (BMSCs) and their combination treatment were demonstrated to have beneficial effects in promoting angiogenesis both in vitro and in vivo. In this review, we summarized the effective mechanisms of Chinese medicines and BMSCs, as well as BMSCs in combination with Chinese medicines on angiogenesis post-stroke. © 2014 World Scientific Publishing Company & Institute for Advanced Research in Asian Science and Medicine.

KeywordAngiogenesis Bone Marrow Stromal Cells Chinese Medicines Combination Treatment Ischemic Stroke Review
DOI10.1142/S0192415X14500049
URLView the original
Indexed BySCI
Language英语
WOS Research AreaIntegrative & Complementary Medicine ; General & Internal Medicine
WOS SubjectIntegrative & Complementary Medicine ; Medicine, General & Internal
WOS IDWOS:000330851200004
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Cited Times [WOS]:18   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorZhao Y.-H.
AffiliationMacau University of Science and Technology
Recommended Citation
GB/T 7714
Zhang Q.,Zhao Y.-H.. Therapeutic angiogenesis after ischemic stroke: Chinese medicines, bone marrow stromal cells (bmscs) and their combinational treatment[J]. American Journal of Chinese Medicine,2014,42(1):61-77.
APA Zhang Q.,&Zhao Y.-H..(2014).Therapeutic angiogenesis after ischemic stroke: Chinese medicines, bone marrow stromal cells (bmscs) and their combinational treatment.American Journal of Chinese Medicine,42(1),61-77.
MLA Zhang Q.,et al."Therapeutic angiogenesis after ischemic stroke: Chinese medicines, bone marrow stromal cells (bmscs) and their combinational treatment".American Journal of Chinese Medicine 42.1(2014):61-77.
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