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Sulfation of tea polysaccharides: Synthesis, characterization and hypoglycemic activity
Wang Y.2; Peng Y.1; Wei X.2; Yang Z.2; Xiao J.2; Jin Z.1
2010-03-01
Source PublicationInternational Journal of Biological Macromolecules
ISSN01418130
Volume46Issue:2Pages:270-274
Abstract

Neutral polysaccharides (NTPS) and acid polysaccharides (ATPS) from tea leaves were obtained on a D315 macroporous anion-exchange resin column chromatography. NTPS and ATPS were sulfated by the pyridine-sulfonic acid method to obtain NTPS-S and ATPS-S. It was found that NTPS was easier sulfated than ATPS. There are strong characteristic absorption peaks located in 1258cm, 1146cm, 832cm and 617cm in the FTIR spectra of sulfated polysaccharides. Sulfation of polysaccharides also affected the endothermic and exothermic peaks via the DSC scan analysis. The appearance of exothermic peaks in both NTPS-S and ATPS-S indicated that the redox reaction might happen. The comparative study of hypoglycemic effect on mice showed that the sulfation of polysaccharides significantly improved hypoglycemic activity.

KeywordCharacterization Hypoglycemic Activity Sulfation Synthesis Tea Polysaccharides
DOI10.1016/j.ijbiomac.2009.12.007
URLView the original
Indexed BySCIE
Language英语
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry ; Polymer Science
WOS SubjectBiochemistry & Molecular Biology ; Chemistry, Applied ; Polymer Science
WOS IDWos:000275700900024
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Cited Times [WOS]:51   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.Jiangnan University
2.Shanghai Normal University
Recommended Citation
GB/T 7714
Wang Y.,Peng Y.,Wei X.,et al. Sulfation of tea polysaccharides: Synthesis, characterization and hypoglycemic activity[J]. International Journal of Biological Macromolecules,2010,46(2):270-274.
APA Wang Y.,Peng Y.,Wei X.,Yang Z.,Xiao J.,&Jin Z..(2010).Sulfation of tea polysaccharides: Synthesis, characterization and hypoglycemic activity.International Journal of Biological Macromolecules,46(2),270-274.
MLA Wang Y.,et al."Sulfation of tea polysaccharides: Synthesis, characterization and hypoglycemic activity".International Journal of Biological Macromolecules 46.2(2010):270-274.
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