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Effect of ZnO#ZnS QDs heterojunctures on the stilbenes-plasma proteins interactions
Xiao J.2; Wang F.2; Liu J.2; Wang L.2; Kai G.2; Yu X.2
2011-08-01
Source PublicationMolecular BioSystems
ISSN1742206X 17422051
Volume7Issue:8Pages:2452-2458
AbstractZero-dimensional nanostructures such as ZnO#ZnS QDs heterojunctures (QDHJs) are green nanoparticles and have gained a tremendous amount of attention. However, very little information is available on the effects of these heterojunctures on the transportation of drugs in blood. Herein, stilbenes were studied for their affinities for common bovine plasma proteins (CBPP) in the presence and absence of QDHJs with different diameters. The affinities of QDHJs for CBPP improved with increasing QDHJs size. QDHJs improved the affinities of resveratrol and polydatin for CBPP by 14.74% to 22.36% and 12.56% to 21.34% depending on the size of QDHJs. The number of binding sites (n) between resveratrol and polydatin for CBPP in the presence of QDHJs were 1.04 ± 0.03 and 1.06 ± 0.04, which were obviously higher than those in the absence of QDHJs (n = 0.89 and 0.92). QDHJs in blood will decrease the free concentration of stilbenes and weaken their pharmacological effects. © The Royal Society of Chemistry 2011.
DOI10.1039/c1mb05087g
URLView the original
Language英語
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Cited Times [WOS]:6   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
Affiliation1.Okayama Prefectural University
2.Shanghai Normal University
Recommended Citation
GB/T 7714
Xiao J.,Wang F.,Liu J.,et al. Effect of ZnO#ZnS QDs heterojunctures on the stilbenes-plasma proteins interactions[J]. Molecular BioSystems,2011,7(8):2452-2458.
APA Xiao J.,Wang F.,Liu J.,Wang L.,Kai G.,&Yu X..(2011).Effect of ZnO#ZnS QDs heterojunctures on the stilbenes-plasma proteins interactions.Molecular BioSystems,7(8),2452-2458.
MLA Xiao J.,et al."Effect of ZnO#ZnS QDs heterojunctures on the stilbenes-plasma proteins interactions".Molecular BioSystems 7.8(2011):2452-2458.
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