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Seeing the unseen of Chinese herbal medicine processing (Paozhi): advances in new perspectives
Wu, Xu; Wang, Shengpeng; Lu, Junrong; Jing, Yong; Li, Mingxing; Cao, Jiliang; Bian, Baolin; Hu, Changjiang
2018-01-17
Source PublicationCHINESE MEDICINE
ISSN1749-8546
Volume13
AbstractProcessing (Paozhi) represents a unique Chinese pharmaceutic technique to facilitate the use of Chinese herbal medicines (CHMs) for a specific clinical need in the guidance of Traditional Chinese Medicine (TCM) theory. Traditionally, most CHMs require a proper processing to meet the needs of specific clinical syndromes before being prescribed by TCM practitioners. During processing, significant changes in chemical profiles occur, which inevitably influence the associated pharmacological properties of a CHM. However, although processing is formed in a long-term practice, the underlying mechanisms remain unclear for most CHMs. The deepening understanding of the mechanism of processing would provide scientific basis for standardization of processing. This review introduced the role of processing in TCM and several typical methods of processing. We also summarized the up-to-date efforts on the mechanistic study of CHM processing. The processing mechanisms mainly include the following aspects: (i) directly reducing contents of toxic constituents; (ii) structural transformation of constituents; (iii) improving solubility of constituents; (iv) physically changing the existing form of constituents; (v) and influence by excipients. These progress may give new insights into future researches.
KeywordProcessing Chinese herbal medicines Decoction pieces Standardization Mechanism
DOI10.1186/s13020-018-0163-3
URLView the original
Indexed BySCI
Language英语
WOS Research AreaIntegrative & Complementary Medicine ; Pharmacology & Pharmacy
WOS SubjectIntegrative & Complementary Medicine ; Pharmacology & Pharmacy
WOS IDWOS:000422731300001
PublisherBIOMED CENTRAL LTD
The Source to ArticleWOS
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被引频次[WOS]:8   [WOS记录]     [WOS相关记录]
Document TypeJournal article
专题University of Macau
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GB/T 7714
Wu, Xu,Wang, Shengpeng,Lu, Junrong,et al. Seeing the unseen of Chinese herbal medicine processing (Paozhi): advances in new perspectives[J]. CHINESE MEDICINE,2018,13.
APA Wu, Xu.,Wang, Shengpeng.,Lu, Junrong.,Jing, Yong.,Li, Mingxing.,...&Hu, Changjiang.(2018).Seeing the unseen of Chinese herbal medicine processing (Paozhi): advances in new perspectives.CHINESE MEDICINE,13.
MLA Wu, Xu,et al."Seeing the unseen of Chinese herbal medicine processing (Paozhi): advances in new perspectives".CHINESE MEDICINE 13(2018).
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