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Seasonal dynamics of the phytochemical constituents and bioactivities of extracts from Stenoloma chusanum (L.) Ching
Wu S.1; Li J.1; Wang Q.1,2; Cao H.3; Cao J.1; Xiao J.3,4
2017-10-01
Source PublicationFood and Chemical Toxicology
ISSN18736351 02786915
Volume108Pages:458-466
Abstract

Stenoloma chusanum is a traditional Chinese medicinal herb with a very high total flavonoid content (TFC). The seasonal dynamics of the TFC and total phenolic content (TPC) in S. chusanum, as well as antioxidant activity, were investigated. The TFC and TPC showed clear seasonal dynamics, reaching their maxima (24.63 ± 1.34% and 9.58 ± 0.41%, respectively) in February. The TFC and TPC in the aerial parts of the plant were much higher than those in the subterranean parts; however, the antioxidant activities of the extracts from the subterranean parts were slightly higher than those from the aerial parts. Moreover, the extracts exhibited higher inhibition against tyrosinase than against arbutin (the positive control). The extract from S. chusanum collected in February was associated with the highest proliferation and apoptosis of K562 cells. The phytochemicals in the extract were analyzed using LC-MS, and were found to comprise of 12 flavonoids, five alkaloids, one sesquiterpenoid and one phenypropanoid. In conclusion, S. chusanum exhibits multiple bioactivities; these results could contribute to the therapeutic application of the plants in indigenous medicine.

KeywordAnti-tumor Activity Anti-tyrosinase Activity Antioxidant Activity Flavonoids Stenoloma Chusanum
DOI10.1016/j.fct.2016.10.003
URLView the original
Indexed BySCIE
Language英语
WOS Research AreaFood Science & Technology ; Toxicology
WOS SubjectFood Science & Technology ; Toxicology
WOS IDWOS:000413135100011
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Cited Times [WOS]:12   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorCao J.; Xiao J.
Affiliation1.College of Life & Environment Sciences, Shanghai Normal University, Shanghai 200234, China
2.Shanghai Key Laboratory of Plant Functional Genomics & Resource, Shanghai Chenshan Botanical Garden, Shanghai 201602, China
3.Institute of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Avenida da Universidade, Taipa, Macau
4.College of Food Science, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, China
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Wu S.,Li J.,Wang Q.,et al. Seasonal dynamics of the phytochemical constituents and bioactivities of extracts from Stenoloma chusanum (L.) Ching[J]. Food and Chemical Toxicology,2017,108:458-466.
APA Wu S.,Li J.,Wang Q.,Cao H.,Cao J.,&Xiao J..(2017).Seasonal dynamics of the phytochemical constituents and bioactivities of extracts from Stenoloma chusanum (L.) Ching.Food and Chemical Toxicology,108,458-466.
MLA Wu S.,et al."Seasonal dynamics of the phytochemical constituents and bioactivities of extracts from Stenoloma chusanum (L.) Ching".Food and Chemical Toxicology 108(2017):458-466.
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