UM  > 健康科學學院
Extragastrointestinal functions and transcriptional regulation of secretin and secretin receptors
Yuan Y.; Lee L.T.O.; Ng S.S.; Chow B.K.C.
2011
Source PublicationAnnals of the New York Academy of Sciences
ISSN17496632 00778923
Volume1220Issue:1Pages:23-33
AbstractThe functional role of secretin outside the gastrointestinal system has been a mystery to endocrinologists for many years. With the availability of secretin- and secretin receptor-knockout models and the advances of electrophysiological and immunohistochemical techniques, we are now in a good position to explore the functions of secretin outside the gastrointestinal system. There is growing evidence to support that secretin works pleiotropically at multiple levels in our body. In this paper, we review the recent findings regarding the physiological effects of secretin on extragastrointestinal sites including the cerebellum, the hippocampus, and the hypothalamus-pituitary-kidney axis. To understand the mechanisms underlying the site-specific expression of secretin and secretin receptors in the central nervous system, we also discuss the transcriptional regulation of secretin and secretin receptor genes in neuronal cell lines. © 2011 New York Academy of Sciences.
KeywordCentral nervous system Secretin Secretin receptors Transcriptional regulation Water homeostasis
DOI10.1111/j.1749-6632.2011.05987.x
URLView the original
Language英語
Fulltext Access
Citation statistics
Cited Times [WOS]:3   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
AffiliationThe University of Hong Kong
Recommended Citation
GB/T 7714
Yuan Y.,Lee L.T.O.,Ng S.S.,et al. Extragastrointestinal functions and transcriptional regulation of secretin and secretin receptors[J]. Annals of the New York Academy of Sciences,2011,1220(1):23-33.
APA Yuan Y.,Lee L.T.O.,Ng S.S.,&Chow B.K.C..(2011).Extragastrointestinal functions and transcriptional regulation of secretin and secretin receptors.Annals of the New York Academy of Sciences,1220(1),23-33.
MLA Yuan Y.,et al."Extragastrointestinal functions and transcriptional regulation of secretin and secretin receptors".Annals of the New York Academy of Sciences 1220.1(2011):23-33.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Yuan Y.]'s Articles
[Lee L.T.O.]'s Articles
[Ng S.S.]'s Articles
Baidu academic
Similar articles in Baidu academic
[Yuan Y.]'s Articles
[Lee L.T.O.]'s Articles
[Ng S.S.]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Yuan Y.]'s Articles
[Lee L.T.O.]'s Articles
[Ng S.S.]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.