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Are by-products from beeswax recycling process a new promising source of bioactive compounds with biomedical properties?
Giampieri, Francesca1; Quiles, Jose L.2; Orantes-Bermejo, Francisco J.3; Gasparrini, Massimiliano1; Forbes-Hernandez, Tamara Y.1; Sanchez-Gonzalez, Cristina2; Llopis, Juan2; Rivas-Garcia, Lorenzo2; Afrin, Sadia1; Varela-Lopez, Alfonso1; Cianciosi, Danila1; Reboredo-Rodriguez, Patricia1,4; Torres Fernandez-Pinar, Cristina3; Calderon Iglesias, Ruben5; Ruiz, Roberto5; Aparicio, Silvia5; Crespo, Jorge5; Dzul Lopez, Luis6; Xiao, Jianbo7; Battino, Maurizio1,5
2018-02
Source PublicationFOOD AND CHEMICAL TOXICOLOGY
ISSN0278-6915
Volume112Pages:126-133
Abstract

During the process of beeswax recycling, many industrial derivatives are obtained. These matrices may have an interesting healthy and commercial potential but to date they have not been properly studied. The aim of the present work was to evaluate the proximal and phytochemical composition, the antioxidant capacity and cytotoxic effects of two by-products from beeswax recycling process named MUD 1 and MUD 2 on liver hepatocellular carcinoma. Our results showed that MUD 1 presented the highest (P < .05) fiber, protein, carbohydrate, polyphenol and flavonoid concentration, as well as the highest (P < .05) total antioxidant capacity than the MUD 2 samples. MUD1 exerted also anticancer activity on HepG2 cells, by reducing cellular viability, increasing intracellular ROS levels and affecting mitochondrial functionality in a dose-dependent manner.

KeywordHoney Beeswax Food Waste Recycling Process Chemical And phytoChemical Composition Biological Properties
DOI10.1016/j.fct.2017.12.041
URLView the original
Indexed BySCI
Language英语
WOS Research AreaFood Science & Technology ; Toxicology
WOS SubjectFood Science & Technology ; Toxicology
WOS IDWOS:000425568900014
PublisherPERGAMON-ELSEVIER SCIENCE LTD
The Source to ArticleWOS
Fulltext Access
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Cited Times [WOS]:12   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.Department of Clinical Sciences, Faculty of Medicine, Polytechnic University of Marche, Via Ranieri 65, Ancona, 60131, Italy
2.Department of Physiology, Institute of Nutrition and Food Technology “José Mataix”, Biomedical Research Center, University of Granada, Avda del Conocimiento sn., 18100-Armilla, Granada, Spain
3.Apinevada Analytical Laboratory of Bee Products, Barrancos s/n, 18420 Lanjarón, Granada, Spain
4.Departamento de Química Analítica y Alimentaria, Grupo de Nutrición y Bromatología, Universidade de Vigo, Ourense 32004, Spain
5.Center for Nutrition & Health, CITICAN, Universidad Europea del Atlántico, Parque Científico y Tecnológico de Cantabria, C/Isabel Torres 21, 39011 Santander, Spain
6.Universidad Internacional Iberoamericana (UNINI), Campeche, Mexico
7.Instituite of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Taipa, Macau, China
Recommended Citation
GB/T 7714
Giampieri, Francesca,Quiles, Jose L.,Orantes-Bermejo, Francisco J.,et al. Are by-products from beeswax recycling process a new promising source of bioactive compounds with biomedical properties?[J]. FOOD AND CHEMICAL TOXICOLOGY,2018,112:126-133.
APA Giampieri, Francesca.,Quiles, Jose L..,Orantes-Bermejo, Francisco J..,Gasparrini, Massimiliano.,Forbes-Hernandez, Tamara Y..,...&Battino, Maurizio.(2018).Are by-products from beeswax recycling process a new promising source of bioactive compounds with biomedical properties?.FOOD AND CHEMICAL TOXICOLOGY,112,126-133.
MLA Giampieri, Francesca,et al."Are by-products from beeswax recycling process a new promising source of bioactive compounds with biomedical properties?".FOOD AND CHEMICAL TOXICOLOGY 112(2018):126-133.
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