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The prevalence of bipolar disorder in China: A meta-analysis.
Zhang L1; Cao XL2; Wang SB3; Zheng W4; Ungvari GS5; Ng CH6; Zhong BL7; Wang G8; Xiang YT9
2017
Source PublicationJOURNAL OF AFFECTIVE DISORDERS
ISSN0165-0327
Volume207Pages:413-421
Abstract

OBJECTIVE:

This is a meta-analysis of the prevalence of bipolar disorders (BD) in the general population of China.

METHODS:

A systematic literature search was conducted via the following databases: PubMed, EMBASE, PsycINFO, China National Knowledge Infrastructure (CNKI), WanFang and SinoMed. Studies on the prevalence of BD in the general population in China were identified. Statistical analyses were performed using the Comprehensive Meta-Analysis program.

RESULTS:

Altogether 32 studies conducted between 1984 and 2013 with 470,411 participants met the inclusion criteria for the analysis; the median age was 44.6 years and 49.6% of participants were female. The estimated point, 12-month and lifetime prevalence of BD in China were 0.09% (95% Confidence interval [CI]: 0.06-0.12%), 0.17% (95% CI: 0.10-0.29%) and 0.11% (95% CI: 0.07-0.17%), respectively. For BD-I, the estimated point, 12-month and lifetime prevalence rates were 0.06% (95% CI: 0.04-0.10%), 0.08% (95% CI: 0.02-0.30%) and 0.09% (95% CI: 0.05-0.16%), respectively. For BD-II, the estimated point and lifetime prevalence rates were 0.04% (95% CI: 0.02-0.06%) and 0.04% (95% CI: 0.02-0.09%), respectively. The 12-month prevalence of BD before the year 2010 was significantly lower than that after 2010 (0.12% vs. 0.26%, P=0.04). Meta-regression analysis revealed that younger age was significantly associated with higher 12-month prevalence of BD (coefficient=0.096, 95% CI: 0.027, 0.164, P=0.006).

CONCLUSION:

This first meta-analysis of the pooled prevalence of BD in China found that rates are generally lower than those reported in Western countries. Future studies with more rigorous and refined methodology are needed.

KeywordBipolar Disorder Prevalence Meta-analysis China
DOIhttps://doi.org/10.1016/j.jad.2016.08.062
Indexed BySCI
Language英语
WOS Research AreaNeurosciences & Neurology ; Psychiatry
WOS SubjectClinical Neurology ; Psychiatry
WOS IDWOS:000389088600058
Fulltext Access
Citation statistics
Cited Times [WOS]:14   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Affiliation1.The National Clinical Research Center for Mental Disorders, China & Center of Depression, Beijing Institute for Brain Disorders & Mood Disorders Center, Beijing Anding Hospital, Capital Medical University, Beijing, China; Unit of Psychiatry, Faculty of Hea
2.The National Clinical Research Center for Mental Disorders, China & Center of Depression, Beijing Institute for Brain Disorders & Mood Disorders Center, Beijing Anding Hospital, Capital Medical University, Beijing, China; Unit of Psychiatry, Faculty of Health Sciences, University of Macau, Macao SAR, China.
3.Unit of Psychiatry, Faculty of Health Sciences, University of Macau, Macao SAR, China.
4.The Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital), Guangzhou, China.
5.The University of Notre Dame Australia/Marian Centre, Perth, Australia; School of Psychiatry & Clinical Neurosciences, University of Western Australia, Perth, Australia.
6.Department of Psychiatry, University of Melbourne, Melbourne, Victoria, Australia.
7.The Affiliated Mental Health Center, Tongji Medical College of Huazhong University of Science & Technology, Wuhan, China.
8.The National Clinical Research Center for Mental Disorders, China & Center of Depression, Beijing Institute for Brain Disorders & Mood Disorders Center, Beijing Anding Hospital, Capital Medical University, Beijing, China.
9.Unit of Psychiatry, Faculty of Health Sciences, University of Macau, Macao SAR, China.
Recommended Citation
GB/T 7714
Zhang L,Cao XL,Wang SB,et al. The prevalence of bipolar disorder in China: A meta-analysis.[J]. JOURNAL OF AFFECTIVE DISORDERS,2017,207:413-421.
APA Zhang L.,Cao XL.,Wang SB.,Zheng W.,Ungvari GS.,...&Xiang YT.(2017).The prevalence of bipolar disorder in China: A meta-analysis..JOURNAL OF AFFECTIVE DISORDERS,207,413-421.
MLA Zhang L,et al."The prevalence of bipolar disorder in China: A meta-analysis.".JOURNAL OF AFFECTIVE DISORDERS 207(2017):413-421.
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