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Pharmacological actions of Uncaria alkaloids, rhynchophylline and isorhynchophylline
SHI Jing-Shan; YU Jun-Xian; CHEN Xiu-Ping; XU Rui-Xia
2003-02
Source PublicationActa Pharmacologica Sinica
ISSN1671-4083
Volume24Issue:2Pages:97-101
Abstract

The pharmacological actions of Uncaria alkaloids, rhynchophylline and isorhynchophylline extracted from Uncaria rhynchophylla Miq Jacks were reviewed. The alkaloids mainly act on cardiovascular system and central nervous system including the hypotension, brachycardia, antiarrhythmia, and protection of cerebral ischemia and sedation. The active mechanisms were related to blocking of calcium channel, opening of potassium channel, and regulating of nerve transmitters transport and metabolism, etc.

KeywordUncaria Rhynchophylla Isorhynchophylline Herbal Medicine Hypertension Arrhythmia Calcium Hypnotics And Sedatives Rhynchophylline
Language英语
WOS Research AreaChemistry ; Pharmacology & Pharmacy
WOS SubjectChemistry, Multidisciplinary ; Pharmacology & Pharmacy
WOS IDWOS:000180647500001
PublisherSHANGHAI INST MATERIA MEDICA, 555 ZU CHONG ZHI RD, ZHANG JIANG HI-TECH PARK, SHANGHAI, PUDONG 201203, PEOPLES R CHINA
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Citation statistics
Cited Times [WOS]:98   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorSHI Jing-Shan
AffiliationDepartment of Pharmacology, Zunyi Medical College, Zunyi 563003, China
Recommended Citation
GB/T 7714
SHI Jing-Shan,YU Jun-Xian,CHEN Xiu-Ping,et al. Pharmacological actions of Uncaria alkaloids, rhynchophylline and isorhynchophylline[J]. Acta Pharmacologica Sinica,2003,24(2):97-101.
APA SHI Jing-Shan,YU Jun-Xian,CHEN Xiu-Ping,&XU Rui-Xia.(2003).Pharmacological actions of Uncaria alkaloids, rhynchophylline and isorhynchophylline.Acta Pharmacologica Sinica,24(2),97-101.
MLA SHI Jing-Shan,et al."Pharmacological actions of Uncaria alkaloids, rhynchophylline and isorhynchophylline".Acta Pharmacologica Sinica 24.2(2003):97-101.
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