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The Chemical Constituents and Bioactivities of Psoralea corylifolia Linn.: A Review
Zhang X1,2; Zhao W2; Wang Y2; Lu J2; Chen X2
2016-02-02
Source PublicationThe American Journal of Chinese Medicine
ISSN0192-415X
Volume44Issue:1Pages:35-60
Abstract

Psoralea corylifolia Linn. (P. corylifolia) is an important medicinal plant with thousands of years of clinical application. It has been widely used in many traditional Chinese medicine formulas for the treatment of various diseases such as leucoderma and other skin diseases, cardiovascular diseases, nephritis, osteoporosis, and cancer. Phytochemical studies indicated that coumarins, flavonoids, and meroterpenes are the main components of P. corylifolia, and most of these components are present in the seeds or fruits. The extracts and active components of P. corylifolia demonstrated multiple biological activities, including estrogenic, antitumor, anti-oxidant, antimicrobial, antidepressant, antiinflammatory, osteoblastic, and hepatoprotective activities. This paper systematically summarized literatures on the chemical constituents and biological activities of P. corylifolia, which provided useful information for the further research and development toward this potent medicinal plant.

KeywordPsoraL.a CoryL.foL.a L. Chemical Constituents Coumarins Flavovoids Meroterpenes Biological Activities
DOIhttps://doi.org/10.1142/S0192415X16500038
Indexed BySCI
Language英语
WOS Research AreaIntegrative & Complementary Medicine ; General & Internal Medicine
WOS SubjectIntegrative & Complementary Medicine ; Medicine, General & Internal
WOS IDWOS:000371324400003
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Cited Times [WOS]:29   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.Department of Pharmacy, The First College of Clinical Medical Science, China Three Gorges University, Yichang, Hubei, China
2.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, China
First Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Zhang X,Zhao W,Wang Y,et al. The Chemical Constituents and Bioactivities of Psoralea corylifolia Linn.: A Review[J]. The American Journal of Chinese Medicine,2016,44(1):35-60.
APA Zhang X,Zhao W,Wang Y,Lu J,&Chen X.(2016).The Chemical Constituents and Bioactivities of Psoralea corylifolia Linn.: A Review.The American Journal of Chinese Medicine,44(1),35-60.
MLA Zhang X,et al."The Chemical Constituents and Bioactivities of Psoralea corylifolia Linn.: A Review".The American Journal of Chinese Medicine 44.1(2016):35-60.
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