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Identification of Salvia species using high-performance liquid chromatography combined with chemical pattern recognition analysis
Wang, Yang; Jiang, Kun; Wang, Lijun; Han, Dongqi; Yin, Guo; Wang, Jue; Qin, Bin; Li, Shaoping; Wang, Tiejie
2018-02
Source PublicationJOURNAL OF SEPARATION SCIENCE
ISSN1615-9306
Volume41Issue:3Pages:609-617
AbstractSalvia miltiorrhiza, also known as Danshen, is a widely used traditional Chinese medicine for the treatment of cardiovascular diseases and hematological abnormalities. The root and rhizome of Salvia przewalskii and Salvia yunnanensis have been found as substitutes for Salvia miltiorrhiza in the market. In this study, the chemical information of 14 major compounds in Salvia miltiorrhiza and its substitutes were determined using a high-performance liquid chromatography method. Stepwise discriminant analysis was adopted to select the characteristic variables. Partial least squares discriminant and hierarchical cluster analysis were performed to classify Salvia miltiorrhiza and its substitutes. The results showed that all of the samples were correctly classified both in partial least squares discriminant analysis and hierarchical cluster analysis based on the four compounds (caffeic acid, rosmarinic acid, salvianolic acid B, and salvianolic acid A). This method can not only distinguish Salvia miltiorrhiza and its substitutes, but also classify Salvia przewalskii and Salvia yunnanensis. The method can be applied for the quality assessment of Salvia miltiorrhiza and identification of unknown samples.
Keywordchemical pattern recognition high-performance liquid chromatography Salvia traditional Chinese medicine
DOI10.1002/jssc.201701066
URLView the original
Indexed BySCI
Language英语
WOS Research AreaChemistry
WOS SubjectChemistry, Analytical
WOS IDWOS:000424166600001
PublisherWILEY-V C H VERLAG GMBH
The Source to ArticleWOS
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Cited Times [WOS]:1   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Wang, Yang,Jiang, Kun,Wang, Lijun,et al. Identification of Salvia species using high-performance liquid chromatography combined with chemical pattern recognition analysis[J]. JOURNAL OF SEPARATION SCIENCE,2018,41(3):609-617.
APA Wang, Yang.,Jiang, Kun.,Wang, Lijun.,Han, Dongqi.,Yin, Guo.,...&Wang, Tiejie.(2018).Identification of Salvia species using high-performance liquid chromatography combined with chemical pattern recognition analysis.JOURNAL OF SEPARATION SCIENCE,41(3),609-617.
MLA Wang, Yang,et al."Identification of Salvia species using high-performance liquid chromatography combined with chemical pattern recognition analysis".JOURNAL OF SEPARATION SCIENCE 41.3(2018):609-617.
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