UM  > 中華醫藥研究院
Prospects of Poria cocos polysaccharides: Isolation process, structural features and bioactivities
Jia, Xuejing; Ma, Lishuai; Li, Peng; Chen, Meiwan; He, Chengwei
2016-08
Source PublicationTrends in Food Science & Technology
ISSN0924-2244
Volume54Pages:52-62
Abstract

Background

Poria cocos (Schw.) Wolf possesses therapeutic potential of diuretic, phlegm, and uneasiness of mind in ethnomedicine. Polysaccharides, one kind of the major active ingredients of P. cocos, are considered to be responsible for their versatile use. Now, a systematic summary of research progress and future prospects of polysaccharides from P. cocos (PCPs) are necessary to facilitate their further study and application.

Scope and Approach

In this review, we emphasize the optimal extraction and purification methods, structural features, and biological activities of PCPs. The structure-activity relationships (SAR) is also analyzed and summarized.

Key Findings and Conclusions

Ultrasonic, microwave, enzyme assisted and supercritical carbon dioxide methods have been used to extract PCPs. Among them, ultrasonic technique is the most efficient. PCPs exhibited various bioactivities, including immunomodulation, anti-inflammation, anti-angiogenesis and anticancer. SAR reveal that water solubility, molecular weight, and chain conformation of PCPs are closely related to its biological activity. However, new method for purification of certain polysaccharides, detailed SAR, mechanisms of bioactivities, and quality control of PCPs need to be extensively investigated.

KeywordPoria Cocos Polysaccharide Extraction Structural Features Biological Activities
DOIhttps://doi.org/10.1016/j.tifs.2016.05.021
Indexed BySCI
Language英语
WOS Research AreaFood Science & Technology
WOS SubjectFood Science & Technology
WOS IDWOS:000380603400005
Fulltext Access
Citation statistics
Cited Times [WOS]:24   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorChen, Meiwan; He, Chengwei
AffiliationState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China
First Author AffilicationInstitute of Chinese Medical Sciences
Corresponding Author AffilicationInstitute of Chinese Medical Sciences
Recommended Citation
GB/T 7714
Jia, Xuejing,Ma, Lishuai,Li, Peng,et al. Prospects of Poria cocos polysaccharides: Isolation process, structural features and bioactivities[J]. Trends in Food Science & Technology,2016,54:52-62.
APA Jia, Xuejing,Ma, Lishuai,Li, Peng,Chen, Meiwan,&He, Chengwei.(2016).Prospects of Poria cocos polysaccharides: Isolation process, structural features and bioactivities.Trends in Food Science & Technology,54,52-62.
MLA Jia, Xuejing,et al."Prospects of Poria cocos polysaccharides: Isolation process, structural features and bioactivities".Trends in Food Science & Technology 54(2016):52-62.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Jia, Xuejing]'s Articles
[Ma, Lishuai]'s Articles
[Li, Peng]'s Articles
Baidu academic
Similar articles in Baidu academic
[Jia, Xuejing]'s Articles
[Ma, Lishuai]'s Articles
[Li, Peng]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Jia, Xuejing]'s Articles
[Ma, Lishuai]'s Articles
[Li, Peng]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.