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Prevalence of suicide attempt in individuals with major depressive disorder: a meta-analysis of observational surveys
Dong M1; Zeng LN2; Lu L1; Li XH3; Ungvari GS4; Ng CH5; Chow IHI1; Zhang L6; Zhou Y7; Xiang YT1
2018
Source PublicationPsychol Med
ISSN0033-2917
Abstract

BACKGROUND:

Suicide attempt (SA), which is one of the strongest predictors of completed suicide, is common in major depressive disorder (MDD) but its prevalence across epidemiological studies has been mixed. The aim of this comprehensive meta-analysis was to examine the pooled prevalence of SA in individuals with MDD.

METHODS:

A systematic literature search was conducted in PubMed, Embase, PsycINFO, Web of Science and Cochrane Library from their commencement date until 27 December 2017. Original studies containing data on prevalence of SA in individuals with MDD were analyzed.

RESULTS:

In all, 65 studies with a total of 27 340 individuals with MDD were included. Using the random effects model, the pooled lifetime prevalence of SA was 31% [95% confidence interval (CI) 27-34%], 1-year prevalence was 8% (95% CI 3-14%) and 1-month prevalence was 24% (95% CI 15-34%). Subgroup analyses revealed that the lifetime prevalence of SA was significantly associated with the patient setting, study region and income level, while the 1-month prevalence of SA was associated with only the patient setting.

CONCLUSION:

This meta-analysis confirmed that SA was common in individuals with MDD across the world. Careful screening and appropriate interventions should be implemented for SA in the MDD population.

KeywordMajor Depressive Disorder Suicide Attempt Meta-analysis
DOIhttp://dx.doi.org/10.1017/S0033291718002301
Indexed BySCI
Language英语
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Document TypeJournal article
CollectionFaculty of Health Sciences
Affiliation1.Unit of Psychiatry,Faculty of Health Sciences,University of Macau,Macao SAR,China.
2.Department of Neurosurgery,The Affiliated Hospital of Southwest Medical University,Luzhou,China.
3.The National Clinical Research Center for Mental Disorders, China & Center of Depression, Beijing Institute for Brain Disorders & Mood Disorders Center, Beijing Anding Hospital, Capital Medical University,Beijing,China.
4.University of Notre Dame Australia/Marian Centre,Perth,Australia.
5.Department of Psychiatry,University of Melbourne,Melbourne, Victoria,Australia.
6.Department of Epidemiology and Health Statistics,School of Public Health, Capital Medical University & Beijing Municipal Key Laboratory of Clinical Epidemiology,Beijing,China.
7.CAS Key Laboratory of Behavioral Science & Magnetic Resonance Imaging Research Center, Institute of Psychology, Chinese Academy of Sciences,Beijing,China.
First Author AffilicationFaculty of Health Sciences
Recommended Citation
GB/T 7714
Dong M,Zeng LN,Lu L,et al. Prevalence of suicide attempt in individuals with major depressive disorder: a meta-analysis of observational surveys[J]. Psychol Med,2018.
APA Dong M.,Zeng LN.,Lu L.,Li XH.,Ungvari GS.,...&Xiang YT.(2018).Prevalence of suicide attempt in individuals with major depressive disorder: a meta-analysis of observational surveys.Psychol Med.
MLA Dong M,et al."Prevalence of suicide attempt in individuals with major depressive disorder: a meta-analysis of observational surveys".Psychol Med (2018).
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