UM  > 中華醫藥研究院
Nortriterpenoids from the fruiting bodies of the mushroom Ganoderma resinaceum
Chen X.-Q.1; Chen L.-X.1; Zhao J.1; Tang Y.-P.2; Li S.-P.1
2017-07-01
Source PublicationMolecules
ISSN14203049
Volume22Issue:7
AbstractGanoderma resinaceum is usually used as ethnomedicine for immune-regulation, hyperglycemia, and liver disease. To date, only a few chemical constituents have been reported from G. resinaceum. In this study, fifteen nortriterpenoids including six new nortriterpenoids (1–6) and nine known analogs (7–15), were separated and purified from the fruiting bodies of G. resinaceum. New compounds were identified as lucidone I (1), lucidone J (2), lucidone K (3), lucidone I (4), ganosineniol B (5), and ganosineniol C (6), based on analysis of extensive spectroscopic data (high resolution mass spectrometry (HRMS), nuclear magnetic resonance (NMR), infrared (IR), and ultraviolet (UV)). The known compounds were assigned as lucidone A (7), lucidone B (8), lucidone H (9), lucidone E (10), lucidone F (11), lucidone D (12), lucidone C (13), ganoderense F (14), and ganosineniol A (15), by comparing their spectroscopic data with those reported in the literature. Compounds 3, 4, and 7–13 were examined for α-glucosidase inhibitory activity and display no significant activity, but the finding may support that the side chain of ganoderma triterpenoids played an important role in α-glucosidase inhibitory activity.
KeywordGanoderma resinaceum Lucidones I–L Nortriterpenoid α-glucosidase
DOI10.3390/molecules22071073
URLView the original
Language英語
Fulltext Access
Citation statistics
Cited Times [WOS]:5   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.Universidade de Macau
2.Nanjing University of Traditional Chinese Medicine
Recommended Citation
GB/T 7714
Chen X.-Q.,Chen L.-X.,Zhao J.,et al. Nortriterpenoids from the fruiting bodies of the mushroom Ganoderma resinaceum[J]. Molecules,2017,22(7).
APA Chen X.-Q.,Chen L.-X.,Zhao J.,Tang Y.-P.,&Li S.-P..(2017).Nortriterpenoids from the fruiting bodies of the mushroom Ganoderma resinaceum.Molecules,22(7).
MLA Chen X.-Q.,et al."Nortriterpenoids from the fruiting bodies of the mushroom Ganoderma resinaceum".Molecules 22.7(2017).
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Chen X.-Q.]'s Articles
[Chen L.-X.]'s Articles
[Zhao J.]'s Articles
Baidu academic
Similar articles in Baidu academic
[Chen X.-Q.]'s Articles
[Chen L.-X.]'s Articles
[Zhao J.]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Chen X.-Q.]'s Articles
[Chen L.-X.]'s Articles
[Zhao J.]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.