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Three new 3,4-seco-cycloartane triterpenoids from the flower of Gardenia jasminoides
Zhang, Li-Sha; Wang, Yan-Lan; Liu, Qian; Zhou, Chang-Xin; Mo, Jian-Xia; Lin, Li-Gen; Gan, Li-She
2018-02
Source PublicationPHYTOCHEMISTRY LETTERS
ISSN1874-3900
Volume23Pages:172-175
AbstractThree new 3,4-seco-cycloartane triterpenoids (1-3), including an unusual C-1 oxygenated 3,4-seco-cycloartane triterpenoid lactone (3), along with six known triterpenoids, were isolated from 95% ethanol extract of the flower of Gardenia jasminoides. Their structures were determined by spectroscopic methods, especially 2D NMR and HRESIMS techniques. Compounds 3, 4 (dikamaliartane D), and 7 (ursolic acid) showed promising cytotoxic activity against HepG2 human hepatocellular carcinoma cell line with IC50 values of 9.3, 27.7, and 39.3 mu M, respectively.
KeywordGardenia jasminoides 3,4-seco-Cycloartane triterpenoids Cytotoxic activity
DOI10.1016/j.phytol.2017.11.006
URLView the original
Indexed BySCI
Language英语
WOS Research AreaPlant Sciences ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Medicinal
WOS IDWOS:000426096600032
PublisherELSEVIER SCIENCE BV
The Source to ArticleWOS
Fulltext Access
Citation statistics
Cited Times [WOS]:2   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
Recommended Citation
GB/T 7714
Zhang, Li-Sha,Wang, Yan-Lan,Liu, Qian,et al. Three new 3,4-seco-cycloartane triterpenoids from the flower of Gardenia jasminoides[J]. PHYTOCHEMISTRY LETTERS,2018,23:172-175.
APA Zhang, Li-Sha.,Wang, Yan-Lan.,Liu, Qian.,Zhou, Chang-Xin.,Mo, Jian-Xia.,...&Gan, Li-She.(2018).Three new 3,4-seco-cycloartane triterpenoids from the flower of Gardenia jasminoides.PHYTOCHEMISTRY LETTERS,23,172-175.
MLA Zhang, Li-Sha,et al."Three new 3,4-seco-cycloartane triterpenoids from the flower of Gardenia jasminoides".PHYTOCHEMISTRY LETTERS 23(2018):172-175.
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