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Polygonflavanol A, a novel flavonostilbene glycoside from the roots of Polygonum multiflorum
Chen L.-L.1; Huang X.-J.1; Li M.-M.1; Ou G.-M.1; Zhao B.-X.1; Chen M.-F.1; Zhang Q.-W.2; Wang Y.1; Ye W.-C.1
2012-12-01
Source PublicationPhytochemistry Letters
ISSN18743900 18767486
Volume5Issue:4Pages:756-760
Abstract

Polygonflavanol A (1), a novel flavonostilbene glycoside with an unusual coupling pattern, together with five known stilbene glycosides (2-6), was isolated from the roots of Polygonum multiflorum. The structures were elucidated on the basis of extensive spectroscopic analysis and chemical evidence. The absolute configuration of 1 was further determined by CD analysis. Most of the compounds could inhibit nitric oxide (NO) secretion of RAW264.7 cells in respond to lipopolysaccharide (LPS) in a dose dependent manner. Among them, compound 2 displayed the highest inhibitory activity. © 2012 Phytochemical Society of Europe.

KeywordAnti-inflammatory Flavanostilbene Polygonflavanol a Polygonum Multiflorum Stilbene Glycoside
DOI10.1016/j.phytol.2012.08.007
URLView the original
Indexed BySCI
WOS Research AreaPlant Sciences ; Pharmacology & Pharmacy
WOS SubjectPlant Sciences ; Chemistry, Medicinal
WOS IDWOS:000311337300016
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Cited Times [WOS]:11   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.Jinan University
2.Universidade de Macau
Recommended Citation
GB/T 7714
Chen L.-L.,Huang X.-J.,Li M.-M.,et al. Polygonflavanol A, a novel flavonostilbene glycoside from the roots of Polygonum multiflorum[J]. Phytochemistry Letters,2012,5(4):756-760.
APA Chen L.-L..,Huang X.-J..,Li M.-M..,Ou G.-M..,Zhao B.-X..,...&Ye W.-C..(2012).Polygonflavanol A, a novel flavonostilbene glycoside from the roots of Polygonum multiflorum.Phytochemistry Letters,5(4),756-760.
MLA Chen L.-L.,et al."Polygonflavanol A, a novel flavonostilbene glycoside from the roots of Polygonum multiflorum".Phytochemistry Letters 5.4(2012):756-760.
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