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Steroidal sapogenins and glycosides from the fibrous roots of Ophiopogon japonicus and Liriope spicata var. prolifera with Anti-inflammatory Activity
Qi J.3; Hu Z.-F.3; Zhou Y.-F.3; Hu Y.-J.2; Yu B.-Y.3
2015-03-01
Source PublicationChemical and Pharmaceutical Bulletin
ISSN13475223 00092363
Volume63Issue:3Pages:187-194
AbstractTwo new steroidal glycosides (1 and 2), together with 15 known compounds (3-17) were isolated from the fibrous roots of Ophiopogon japonicus, and three new steroidal glycosides (18-20), together with 14 known compounds (21-34) were isolated from the fibrous roots of Liriope spicata var. prolifera . The structures of the new compounds were elucidated on the basis of extensive one-dimensional (1D)- and 2D-NMR spectroscopic analyses and mass spectrometry. The isolated compounds were evaluated for their anti-inflammatory activity in vitro. Most of these steroidal glycosides showed significant inhibitory activity against neutrophil respiratory burst stimulated by phorbol myristate acetate.
KeywordAnti-inflammatory activity Liriope spicata Ophiopogon japonicus Steroidal glycoside
DOI10.1248/cpb.c14-00735
URLView the original
Language英語
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Cited Times [WOS]:10   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
Affiliation1.Nanjing Pharmaceutical Group Co., Ltd.
2.Universidade de Macau
3.China Pharmaceutical University
Recommended Citation
GB/T 7714
Qi J.,Hu Z.-F.,Zhou Y.-F.,et al. Steroidal sapogenins and glycosides from the fibrous roots of Ophiopogon japonicus and Liriope spicata var. prolifera with Anti-inflammatory Activity[J]. Chemical and Pharmaceutical Bulletin,2015,63(3):187-194.
APA Qi J.,Hu Z.-F.,Zhou Y.-F.,Hu Y.-J.,&Yu B.-Y..(2015).Steroidal sapogenins and glycosides from the fibrous roots of Ophiopogon japonicus and Liriope spicata var. prolifera with Anti-inflammatory Activity.Chemical and Pharmaceutical Bulletin,63(3),187-194.
MLA Qi J.,et al."Steroidal sapogenins and glycosides from the fibrous roots of Ophiopogon japonicus and Liriope spicata var. prolifera with Anti-inflammatory Activity".Chemical and Pharmaceutical Bulletin 63.3(2015):187-194.
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