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Paired Box Protein 6 Alternative Splicing and Corneal Development
Park, Jung Woo; Yang, Juan; Xu, Ren-He
2018-03
Source PublicationSTEM CELLS AND DEVELOPMENT
ISSN1547-3287
Volume27Issue:6Pages:367-377
Abstract

Paired box protein 6 (PAX6) is a master regulator of the eye development. Over the last past two decades, our understanding of eye development, especially the molecular function of PAX6, has focused on transcriptional control of the Pax6 expression. However, other regulatory mechanisms for gene expression, including alternative splicing (AS), have been understudied in the eye development. Recent findings suggest that two PAX6 isoforms generated by AS of Pax6 pre-mRNA may play previously underappreciated role(s) during eye development, especially, the corneal development.

KeywordAlternative Splicing Corneal Development Pax6 Splicing Regulation
DOI10.1089/scd.2017.0283
URLView the original
Indexed BySCI
Language英语
WOS Research AreaCell Biology ; Hematology ; Research & Experimental Medicine ; Transplantation
WOS SubjectCell & Tissue Engineering ; Hematology ; Medicine, Research & Experimental ; Transplantation
WOS IDWOS:000425759800001
PublisherMARY ANN LIEBERT, INC
The Source to ArticleWOS
Fulltext Access
Citation statistics
Document TypeJournal article
CollectionFaculty of Health Sciences
Corresponding AuthorPark, Jung Woo
AffiliationFaculty of Health Sciences, University of Macau , Macau, China
First Author AffilicationFaculty of Health Sciences
Corresponding Author AffilicationFaculty of Health Sciences
Recommended Citation
GB/T 7714
Park, Jung Woo,Yang, Juan,Xu, Ren-He. Paired Box Protein 6 Alternative Splicing and Corneal Development[J]. STEM CELLS AND DEVELOPMENT,2018,27(6):367-377.
APA Park, Jung Woo,Yang, Juan,&Xu, Ren-He.(2018).Paired Box Protein 6 Alternative Splicing and Corneal Development.STEM CELLS AND DEVELOPMENT,27(6),367-377.
MLA Park, Jung Woo,et al."Paired Box Protein 6 Alternative Splicing and Corneal Development".STEM CELLS AND DEVELOPMENT 27.6(2018):367-377.
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