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Psoriasis therapy by Chinese medicine and modern agents
Meng, Shikang1; Lin, Zibei1; Wang, Yan2; Wang, Zhenping3; Li, Ping2,4; Zheng, Ying1
2018-03-23
Source PublicationCHINESE MEDICINE
ISSN1749-8546
Volume13
Abstract

Psoriasis is a chronic, painful, disfiguring and non-contagious skin disease that has globally affected at least 200 million patients. In general, mild to moderate psoriasis patients will be treated by chemical drugs or Chinese medicine, while targeting systemic biological drugs have been successfully developed with good efficacy but high cost burden to patients with severe psoriasis. Since the underlying mechanisms of psoriasis are not well understood, in this review, psoriasis pathogenesis and clinical therapeutic principles by modern medicine and Chinese medicine are extensively described. Based on the data from the China Food and Drug Administration, the majority of chemical drugs are utilized as the topical formulations, while Chinese medicines are mainly delivered by an oral route, suggesting that the market for topical preparations of Chinese medicine to treat psoriasis is worth to exploration. Moreover, considering the unique clinical therapeutic theory and successful clinical application of Chinese medicine in the treatment of psoriasis, we believe that development of new small molecule drugs based on Chinese medicine will be a promising strategy to reduce therapeutic costs and improve safety for psoriatic patients.

KeywordPsoriasis Therapy Chinese Medicine
DOIhttp://doi.org/10.1186/s13020-018-0174-0
URLView the original
Indexed BySCI
Language英语
WOS Research AreaIntegrative & Complementary Medicine ; Pharmacology & Pharmacy
WOS SubjectIntegrative & Complementary Medicine ; Pharmacology & Pharmacy
WOS IDWOS:000428213700001
PublisherBIOMED CENTRAL LTD
The Source to ArticleWOS
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被引频次[WOS]:11   [WOS记录]     [WOS相关记录]
Document TypeJournal article
专题Institute of Chinese Medical Sciences
Corresponding AuthorLi, Ping; Zheng, Ying
Affiliation1.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Science, University of Macau, Macau, China
2.Beijing Hospital of Traditional Chinese Medicine, Afliated with Capital Medical University, Beijing, China
3.Department of Dermatology, School of Medicine, University of California, San Diego, La Jolla, CA, USA
4.Department of Pathophysiology, Beijing Key Laboratory of Clinic and Basic Research with Traditional Chinese Medicine on Psoriasis, Beijing Institute of Traditional Chinese Medicine, 23 Meishuguan Back Street, Dongcheng, Beijing 100010, People’s Republic of China
First Author AffilicationUniversity of Macau
Corresponding Author AffilicationUniversity of Macau
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GB/T 7714
Meng, Shikang,Lin, Zibei,Wang, Yan,et al. Psoriasis therapy by Chinese medicine and modern agents[J]. CHINESE MEDICINE,2018,13.
APA Meng, Shikang,Lin, Zibei,Wang, Yan,Wang, Zhenping,Li, Ping,&Zheng, Ying.(2018).Psoriasis therapy by Chinese medicine and modern agents.CHINESE MEDICINE,13.
MLA Meng, Shikang,et al."Psoriasis therapy by Chinese medicine and modern agents".CHINESE MEDICINE 13(2018).
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