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Evaluation of radiation dose and image quality of CT scan for whole-body pediatric PET/CT: A phantom study
Yang C.-C.1; Liu S.-H.1,2; Mok G.S.P.3; Wu T.-H.4
2014
Source PublicationMedical Physics
ISSN00942405
Volume41Issue:9
Abstract

Purpose: This study aimed to tailor the CT imaging protocols for pediatric patients undergoing whole-body PET/CT examinations with appropriate attention to radiation exposure while maintaining adequate image quality for anatomic delineation of PET findings and attenuation correction of PET emission data. Methods: The measurements were made by using three anthropomorphic phantoms representative of 1-, 5-, and 10-year-old children with tube voltages of 80, 100, and 120 kVp, tube currents of 10, 40, 80, and 120 mA, and exposure time of 0.5 s at 1.75:1 pitch. Radiation dose estimates were derived from the dose-length product and were used to calculate risk estimates for radiation-induced cancer. The influence of image noise on image contrast and attenuation map for CT scans were evaluated based on Pearson's correlation coefficient and covariance, respectively. Multiple linear regression methods were used to investigate the effects of patient age, tube voltage, and tube current on radiation-induced cancer risk and image noise for CT scans. Results: The effective dose obtained using three anthropomorphic phantoms and 12 combinations of kVp and mA ranged from 0.09 to 4.08 mSv. Based on our results, CT scans acquired with 80 kVp/60 mA, 80 kVp/80 mA, and 100 kVp/60 mA could be performed on 1-, 5-, and 10-year-old children, respectively, to minimize cancer risk due to CT scans while maintaining the accuracy of attenuation map and CT image contrast. The effective doses of the proposed protocols for 1-, 5- and 10-year-old children were 0.65, 0.86, and 1.065 mSv, respectively. Conclusions: Low-dose pediatric CT protocols were proposed to balance the tradeoff between radiation-induced cancer risk and image quality for patients ranging in age from 1 to 10 years old undergoing whole-body PET/CT examinations. © 2014 American Association of Physicists in Medicine.

KeywordImage Quality Pediatric Patients Radiation Dose Whole-body Pet/ct
DOIhttp://dx.doi.org/10.1118/1.4893273
URLView the original
Indexed BySCI
Language英语
WOS Research AreaRadiology, Nuclear Medicine & Medical Imaging
WOS SubjectRadiology, Nuclear Medicine & Medical Imaging
WOS IDWOS:000342204800042
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Cited Times [WOS]:4   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Affiliation1.Department of Medical Imaging and Radiological Sciences, Tzu-Chi College of Technology, 970, Hualien,Taiwan
2.Department of Nuclear Medicine, Buddhist Tzu-Chi General Hospital, 970, Hualien, Taiwan
3.Biomedical Imaging Laboratory, Department of Electrical and Computer Engineering, Faculty of Science andTechnology, University of Macau, Macau, China
4.Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, 112, Taipei,Taiwan
Recommended Citation
GB/T 7714
Yang C.-C.,Liu S.-H.,Mok G.S.P.,et al. Evaluation of radiation dose and image quality of CT scan for whole-body pediatric PET/CT: A phantom study[J]. Medical Physics,2014,41(9).
APA Yang C.-C.,Liu S.-H.,Mok G.S.P.,&Wu T.-H..(2014).Evaluation of radiation dose and image quality of CT scan for whole-body pediatric PET/CT: A phantom study.Medical Physics,41(9).
MLA Yang C.-C.,et al."Evaluation of radiation dose and image quality of CT scan for whole-body pediatric PET/CT: A phantom study".Medical Physics 41.9(2014).
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