Use of anticholinergic drugs in patients with schizophrenia in Asia from 2001 to 2009

doi:10.1055/s-0031-1275658

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	Use of anticholinergic drugs in patients with schizophrenia in Asia from 2001 to 2009
	Xiang Y.-T.8 ; Wang C.-Y.4; Si T.-M.12; Lee E.H.M.8; He Y.-L.13; Ungvari G.S.14; Chiu H.F.K.8; Yang S.-Y.5; Chong M.-Y.7; Tan C.-H.6; Kua E.-H.6; Fujii S.2; Sim K.10; Yong K.H.10; Trivedi J.K.9; Chung E.-K.1; Udomratn P.16; Chee K.-Y.3; Sartorius N.11; Shinfuku N.15
	2011-04-15
Source Publication	Pharmacopsychiatry
ISSN	01763679 14390795
Volume	44 Issue:3 Pages:114-118
Abstract	Objective: The aim of this study was to survey the use of anticholinergic medication (ACM) in Asia between 2001 and 2009 and examine its demographic and clinical correlates. Method: A total of 6761 hospitalized schizophrenia patients in 9 Asian countries and territories were examined between 2001 and 2009. The patients socio-demographic and clinical characteristics and the prescriptions of psychotropic drugs were recorded using a standardized protocol and data collection procedure. Results: The frequency of ACM prescription decreased from 66.3% in 2001, to 52.8% in 2004 and 54.6% in 2009, with wide inter-country variations at each time period. Multiple logistic regression analysis of the whole sample showed that patients taking ACM presented with more severe positive, negative, and extrapyramidal symptoms. They were also more likely to receive first-generation and depot antipsychotics and antipsychotic polypharmacy, and less likely to receive second-generation ones. Conclusions: The wide variation in ACM prescription across Asia suggests that a combination of clinical, social, economic and cultural factors play a role in determining the use of these drugs. Regular reviews of ACM use are desirable to reveal the discrepancy between treatment guidelines and clinical practice. © Georg Thieme Verlag KG Stuttgart - New York.
DOI	10.1055/s-0031-1275658
URL	View the original
Language	英語
Fulltext Access	View Full-Text via DOI View Full-Text via Web of Science View Full-Text via Scopus
Citation statistics	Cited Times [WOS]:10 [WOS Record] [Related Records in WOS]
Document Type	Journal article
Collection	Faculty of Health Sciences
Affiliation	1.Seoul Children's Hospital 2.Hyogo Institute for Traumatic Stress 3.Kuala Lumpur Hospital 4.Beijing An Ding Hospital, Capital Medical University 5.Taipei City Hospital Taiwan 6.National University of Singapore 7.Chang Gung University 8.Chinese University of Hong Kong 9.Chhatrapati Shahuji Maharaj Medical University 10.Singapore Institute of Mental Health 11.Université de Genève 12.Peking University 13.Shanghai Mental Health Center 14.University of Notre Dame Australia 15.Seinan Gakuin University 16.Prince of Songkla University
Recommended Citation GB/T 7714	Xiang Y.-T.,Wang C.-Y.,Si T.-M.,et al. Use of anticholinergic drugs in patients with schizophrenia in Asia from 2001 to 2009[J]. Pharmacopsychiatry,2011,44(3):114-118.
APA	Xiang Y.-T..,Wang C.-Y..,Si T.-M..,Lee E.H.M..,He Y.-L..,...&Shinfuku N..(2011).Use of anticholinergic drugs in patients with schizophrenia in Asia from 2001 to 2009.Pharmacopsychiatry,44(3),114-118.
MLA	Xiang Y.-T.,et al."Use of anticholinergic drugs in patients with schizophrenia in Asia from 2001 to 2009".Pharmacopsychiatry 44.3(2011):114-118.

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