| Recent synthetic studies towards natural products via [5+2] cycloaddition reactions | |
Liu, Xin; Hu, Ya-Jian; Fan, Jian-Hong; Zhao, Jing ; Li, Shaoping; Li, Chuang-Chuang
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| 2018-04-07 | |
| Source Publication | ORGANIC CHEMISTRY FRONTIERS
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| ISSN | 2052-4129 |
| Volume | 5Issue:7Pages:1217-1228 |
| Abstract | [5 + 2] Cycloaddition reactions have attracted increasing attention from the chemistry community owing to their utility in the field of natural product synthesis. Recently, a number of natural products with complex skeletons have been obtained with the use of [5 + 2] cycloaddition reactions. The effectiveness of these transformations can be attributed to the constant development of new methodologies and their ingenious applications in synthetic design. [5 + 2] Cycloaddition reactions are frequently followed by other operations, such as cyclocondensation and rearrangement reactions. A newly developed type II intramolecular [5 + 2] cycloaddition offers efficient and straightforward synthesis of many highly functionalized and synthetically challenging bridged cycloheptane bicyclic skeletons. This progress has expanded the scope of target synthetic structures achievable by [5 + 2] cycloadditions and enhanced the usefulness of these reactions in natural product synthesis. In this review, we provide a summary of recent progress regarding synthetic studies towards natural products via [5 + 2] cycloaddition reactions. |
| DOI | 10.1039/c7qo01123g |
| URL | View the original |
| Indexed By | SCI |
| Language | 英语 |
| WOS Research Area | Chemistry |
| WOS Subject | Chemistry, Organic |
| WOS ID | WOS:000428670900025 |
| Publisher | ROYAL SOC CHEMISTRY |
| The Source to Article | WOS |
| Fulltext Access | |
| Citation statistics | |
| Document Type | Journal article |
| Collection | Institute of Chinese Medical Sciences |
| Recommended Citation GB/T 7714 | Liu, Xin,Hu, Ya-Jian,Fan, Jian-Hong,et al. Recent synthetic studies towards natural products via [5+2] cycloaddition reactions[J]. ORGANIC CHEMISTRY FRONTIERS,2018,5(7):1217-1228. |
| APA | Liu, Xin,Hu, Ya-Jian,Fan, Jian-Hong,Zhao, Jing,Li, Shaoping,&Li, Chuang-Chuang.(2018).Recent synthetic studies towards natural products via [5+2] cycloaddition reactions.ORGANIC CHEMISTRY FRONTIERS,5(7),1217-1228. |
| MLA | Liu, Xin,et al."Recent synthetic studies towards natural products via [5+2] cycloaddition reactions".ORGANIC CHEMISTRY FRONTIERS 5.7(2018):1217-1228. |
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