| Common use of anticholinergic medications in older patients with schizophrenia: Findings of the Research on Asian Psychotropic Prescription Pattern (REAP) study, 2001-2009 | |
Xiang Y.-T.13 ; Dickerson F.1; Kreyenbuhl J.7; Ungvari G.S.10; Wang C.-Y.6; Si T.-M.15; Lee E.H.M.13; Chiu H.F.K.13; Lai K.Y.C.13; He Y.-L.16; Yang S.-Y.8; Chong M.-Y.12; Tan C.-H.11; Kua E.-H.11; Fujii S.3; Sim K.2; Yong M.K.H.2; Trivedi J.K.14; Chung E.-K.9; Udomratn P.19; Chee K.-Y.5; Sartorius N.4; Shinfuku N.18
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| 2013-03-01 | |
| Source Publication | International Journal of Geriatric Psychiatry
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| ISSN | 08856230 10991166 |
| Volume | 28Issue:3Pages:305-311 |
| Abstract | Objective This study surveyed the use of anticholinergic medications (ACMs) in older Asian patients with schizophrenia and examined its demographic and clinical correlates. Method A total of 1452 hospitalized patients with schizophrenia aged 55 years or older in nine Asian countries and territories were surveyed between 2001 and 2009. The cross-sectional data of patients' socio-demographic and clinical characteristics and the prescriptions of antipsychotic drugs and ACM were recorded using a standardized protocol and data collection procedure. Results The frequency of ACM prescription was 64.6% in the pooled sample, with 72.4%, 61.9%, and 59.5% in 2001, 2004, and 2009, respectively. Multiple logistic regression analysis of the whole sample revealed that patients on ACM had a higher dose of antipsychotic medications, and were more likely to have extrapyramidal side effects and receive first-generation antipsychotic medications. Conclusions Anticholinergic medications were frequently used in older Asian patients with schizophrenia. Considering the potential side effects of ACM, the rationale for their widespread use in this patient population should be revisited. © 2012 John Wiley & Sons, Ltd. |
| Keyword | anticholinergic Asia older patients prescription patterns schizophrenia |
| DOI | 10.1002/gps.3827 |
| URL | View the original |
| Language | 英語 |
| Fulltext Access | |
| Citation statistics | |
| Document Type | Journal article |
| Collection | Faculty of Health Sciences |
| Affiliation | 1.The Stanley Research Program at Sheppard Pratt 2.Institute of Mental Health 3.Hyogo Institute for Traumatic Stress (HITS) 4.Association for the Improvement of Mental Health Programs 5.Kuala Lumpur Hospital 6.Beijing An Ding Hospital, Capital Medical University 7.University of Maryland School of Medicine 8.Taipei City Hospital Taiwan 9.Seoul National University 10.University of Western Australia 11.National University of Singapore 12.Chang Gung University 13.Chinese University of Hong Kong 14.Chhatrapati Shahuji Maharaj Medical University 15.Peking University 16.Shanghai Mental Health Center 17.VA Medical Center 18.Seinan Gakuin University 19.Prince of Songkla University |
| Recommended Citation GB/T 7714 | Xiang Y.-T.,Dickerson F.,Kreyenbuhl J.,et al. Common use of anticholinergic medications in older patients with schizophrenia: Findings of the Research on Asian Psychotropic Prescription Pattern (REAP) study, 2001-2009[J]. International Journal of Geriatric Psychiatry,2013,28(3):305-311. |
| APA | Xiang Y.-T..,Dickerson F..,Kreyenbuhl J..,Ungvari G.S..,Wang C.-Y..,...&Shinfuku N..(2013).Common use of anticholinergic medications in older patients with schizophrenia: Findings of the Research on Asian Psychotropic Prescription Pattern (REAP) study, 2001-2009.International Journal of Geriatric Psychiatry,28(3),305-311. |
| MLA | Xiang Y.-T.,et al."Common use of anticholinergic medications in older patients with schizophrenia: Findings of the Research on Asian Psychotropic Prescription Pattern (REAP) study, 2001-2009".International Journal of Geriatric Psychiatry 28.3(2013):305-311. |
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