Gender differences in demographic and clinical features and prescribing patterns of psychotropic medications in patients with major depressive disorder in China

doi:10.1016/j.comppsych.2013.04.018

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	Gender differences in demographic and clinical features and prescribing patterns of psychotropic medications in patients with major depressive disorder in China
	Xiang Y.-T.1 ; Wang G.4; Guo T.4; Hu C.4; Ungvari G.S.18; Kilbourne A.M.2; Lai K.Y.C.1; Wong S.Y.S.1; Si T.-M.13; Zheng Q.-W.11; Chen D.-F.11; Fang Y.-R.10; Lu Z.17; Yang H.-C.3; Hu J.6; Chen Z.-Y.5; Huang Y.15; Sun J.7; Wang X.-P.16; Li H.-C.12; Zhang J.-B.14; Chiu H.F.K.1
	2013-11-01
Source Publication	Comprehensive Psychiatry
ISSN	0010440X 15328384
Volume	54 Issue:8 Pages:1198-1202
Abstract	Purpose Little is known about gender differences associated with major depressive disorder (MDD) in China. This study examined gender differences associated with other demographic and clinical characteristics and psychotropic drug treatment in Chinese patients with MDD. Methods A total of 1178 patients with MDD from 13 psychiatric hospitals or psychiatric units of general hospitals in China nationwide were enrolled. Cross-sectional data including patients' demographic and clinical characteristics and prescriptions of psychotropic medications were recorded using a standardized protocol and data collection procedure. Results The sample consisted of 793 female and 385 male patients. Univariate analyses revealed that male patients were younger than female patients, had a younger age of onset of depression, had less lifetime depressive episodes and had more bipolar features (i.e. patients who screened positive for hypomanic symptoms on the 32-item Hypomania Checklist, but did not meet the diagnostic criteria for DSM-IV bipolar disorders as measured by the Mini International Neuropsychiatric Interview). Also, men were more likely to be employed than women and less likely to have depressive episodes following stressful life events. In multivariate analyses, being employed, having bipolar features and not having depressive episodes following stressful life events were independently associated with being a male patient with major depressive disorder. There was no difference in use of psychotropic medications by gender. Conclusions Most gender differences in MDD patients in this study are not consistent with findings of Western studies suggesting that gender differences in MDD may be determined by both biological and sociocultural differences among ethnically different patient populations. © 2013 Elsevier Inc.
DOI	10.1016/j.comppsych.2013.04.018
URL	View the original
Language	英語
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引用统计	被引频次[WOS]：4 [WOS记录] [WOS相关记录]
Document Type	Journal article
专题	Faculty of Health Sciences
Affiliation	1.Chinese University of Hong Kong 2.Veterans Administration Ann Arbor Center for Clinical Management Research 3.Shenzhen Mental Health Centre 4.Beijing An Ding Hospital, Capital Medical University 5.Hangzhou Seventh People's Hospital 6.Harbin Medical University 7.Nanjing Medical University 8.University of Michigan Medical School 9.University of Western Australia 10.Shanghai Jiao Tong University School of Medicine 11.Peking University Health Science Center 12.Zhejiang University 13.Peking University 14.Sun Yat-Sen University 15.West China Hospital of Sichuan University 16.Second Xiangya Hospital of Central-South University 17.Tongji University 18.University of Notre Dame Australia
推荐引用方式 GB/T 7714	Xiang Y.-T.,Wang G.,Guo T.,et al. Gender differences in demographic and clinical features and prescribing patterns of psychotropic medications in patients with major depressive disorder in China[J]. Comprehensive Psychiatry,2013,54(8):1198-1202.
APA	Xiang Y.-T..,Wang G..,Guo T..,Hu C..,Ungvari G.S..,...&Chiu H.F.K..(2013).Gender differences in demographic and clinical features and prescribing patterns of psychotropic medications in patients with major depressive disorder in China.Comprehensive Psychiatry,54(8),1198-1202.
MLA	Xiang Y.-T.,et al."Gender differences in demographic and clinical features and prescribing patterns of psychotropic medications in patients with major depressive disorder in China".Comprehensive Psychiatry 54.8(2013):1198-1202.