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The Chinese first-episode schizophrenia trial: Background and study design
Han X.7; Yuan Y.B.7; Yu X.7; Zhao J.P.9; Wang C.Y.3; Lu Z.5; Yang F.D.2; Dong H.8; Wu Y.F.6; Ungvari G.S.1; Xiang Y.T.10; Chiu H.F.K.4
2014
Source PublicationEast Asian Archives of Psychiatry
ISSN2224-7041 20789947
Volume24Issue:4Pages:169-173
AbstractSchizophrenia is a complex illness with unknown aetiology and pathogenesis. Currently, a considerable number of patients with schizophrenia do not receive standardised and systematic treatment in China. In the past years, many controlled trials have been conducted in chronic schizophrenia. In contrast, research on first-episode schizophrenia is lacking. This paper describes the background and design of the Chinese First-Episode Schizophrenia Trial project - a multicentre, randomised, open-label clinical trial. A total of 600 first-episode schizophrenia patients were randomly divided into 3 groups and treated with risperidone, aripiprazole, and olanzapine for 1 year. During the study period, only 1 medication change of the 3 antipsychotic medications was allowed.
KeywordAntipsychotic agents Clinical trial Schizophrenia
URLView the original
Language英語
Fulltext Access
Document TypeJournal article
CollectionFaculty of Health Sciences
Affiliation1.Notre Dame University
2.Beijing Huilongguan Hospital
3.Beijing An Ding Hospital, Capital Medical University
4.Chinese University of Hong Kong
5.Shanghai Jiao Tong University
6.Peking University Health Science Center
7.Peking University
8.West China Hospital of Sichuan University
9.Second Xiangya Hospital of Central-South University
10.Universidade de Macau
Recommended Citation
GB/T 7714
Han X.,Yuan Y.B.,Yu X.,et al. The Chinese first-episode schizophrenia trial: Background and study design[J]. East Asian Archives of Psychiatry,2014,24(4):169-173.
APA Han X..,Yuan Y.B..,Yu X..,Zhao J.P..,Wang C.Y..,...&Chiu H.F.K..(2014).The Chinese first-episode schizophrenia trial: Background and study design.East Asian Archives of Psychiatry,24(4),169-173.
MLA Han X.,et al."The Chinese first-episode schizophrenia trial: Background and study design".East Asian Archives of Psychiatry 24.4(2014):169-173.
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