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Frequency of Hyperprolactinemia and Its Associations With Demographic and Clinical Characteristics and Antipsychotic Medications in Psychiatric Inpatients in China
Wang Z.-M.2; Xiang Y.-T.4; An F.-R.2; Correll C.U.6; Ungvari G.S.3; Wang C.-Y.2; Lai K.Y.C.4; Bo Q.-J.2; Li Y.4; Zhong B.-L.4; Chiu H.F.K.4
2014
Source PublicationPerspectives in Psychiatric Care
ISSN17446163 00315990
Volume50Issue:4Pages:257-263
Abstract

Purpose: No study has investigated hyperprolactinemia and its risk factors in Chinese psychiatric patients. This study examined the prevalence of hyperprolactinemia and its relationship with demographic and clinical characteristics in inpatients in a large psychiatric institution in Beijing, China. Design and Methods: A consecutive sample of 617 psychiatric inpatients formed the study sample. Basic sociodemographic and clinical data including serum prolactin level were collected. Findings: The prevalence of hyperprolactinemia was 55.9% in the whole sample, and 56.8% and 43.2% for women and men, respectively. The corresponding figures were 59.6%, 40.0%, 53.6%, and 50.8% in schizophrenia spectrum disorders, major depression, bipolar disorders, and other psychiatric disorders, respectively (p = 0.09). In univariate analyses, patients having hyperprolactinemia were younger, more likely to receive risperidone, amisulpride, and first-generation antipsychotics, but less likely to receive clozapine and aripiprazole. In multiple logistic regression analysis, hyperprolactinemia was independently associated with younger age, more use of risperidone or amisulpride and first-generation antipsychotics, and less use of clozapine and aripiprazole (r = 0.197). Practice Implications: Hyperprolactinemia is very common in Chinese psychiatric inpatients. Given the potentially harmful consequences of hyperprolactinemia and its preventable nature, effective measures to lower the frequency hyperprolactinemia in patients with major psychiatric disorders should be implemented in Chinese mental health facilities. Copyright

KeywordAntipsychotic Medication China Hyperprolactinaemia
DOI10.1111/ppc.12050
URLView the original
Indexed BySCI
Language英语
WOS Research AreaNursing ; Psychiatry
WOS SubjectNursing ; Psychiatry
WOS IDWOS:000343996600007
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Cited Times [WOS]:6   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Affiliation1.Marian Centre
2.Beijing An Ding Hospital, Capital Medical University
3.University of Western Australia
4.Chinese University of Hong Kong
5.University of Notre Dame Australia
6.The Zucker Hillside Hospital
Recommended Citation
GB/T 7714
Wang Z.-M.,Xiang Y.-T.,An F.-R.,et al. Frequency of Hyperprolactinemia and Its Associations With Demographic and Clinical Characteristics and Antipsychotic Medications in Psychiatric Inpatients in China[J]. Perspectives in Psychiatric Care,2014,50(4):257-263.
APA Wang Z.-M..,Xiang Y.-T..,An F.-R..,Correll C.U..,Ungvari G.S..,...&Chiu H.F.K..(2014).Frequency of Hyperprolactinemia and Its Associations With Demographic and Clinical Characteristics and Antipsychotic Medications in Psychiatric Inpatients in China.Perspectives in Psychiatric Care,50(4),257-263.
MLA Wang Z.-M.,et al."Frequency of Hyperprolactinemia and Its Associations With Demographic and Clinical Characteristics and Antipsychotic Medications in Psychiatric Inpatients in China".Perspectives in Psychiatric Care 50.4(2014):257-263.
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