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Demographic and clinical differences between early- and late-onset major depressions in thirteen psychiatric institutions in China
Hu C.3; Geng Y.3; Feng Y.3; Wang G.3; Ungvari G.S.17; Chiu H.F.K.8; Kilbourne A.M.1; Lai K.Y.C.8; Si T.-M.12; Zheng Q.-W.10; Fang Y.-R.9; Lu Z.16; Yang H.-C.2; Hu J.5; Chen Z.-Y.4; Huang Y.14; Sun J.6; Wang X.-P.15; Li H.-C.11; Zhang J.-B.13; Xiang Y.-T.18
2015
Source PublicationJournal of Affective Disorders
ISSN15732517 01650327
Volume170Pages:266-269
Abstract

Background Little is known about the demographic and clinical differences between early- and late-onset depressions (EOD and LOD, respectively) in Chinese patients. This study examined the demographic and clinical profile of EOD (<=25 years) compared to LOD (>25 years) in China. Methods A consecutively recruited sample of 1178 patients with MDD was assessed in 13 psychiatric hospitals or psychiatric units of general hospitals in China nationwide. The cross-sectional data of patients demographic and clinical characteristics and prescriptions of psychotropic drugs including antidepressants, mood stabilizers, antipsychotics and benzodiazepines were recorded using a standardized protocol and data collection procedure. Results Two hundred and seventy five (23.3%) of the 1178 patients fulfilled criteria for EOD. In multiple logistic regression analyses, compared to LOD patients their EOD counterparts were more likely to be unmarried and unemployed, had more atypical and psychotic depressive episodes, had bipolar features, while they had more lifetime depressive episodes. Conclusions The demographic and more severe clinical features of EOD in Chinese patients were basically consistent with those found in Western populations. The association between socio-cultural factors and development of EOD warrants further studies.

KeywordEarly Onset Major Depressive Disorder Prescription Patterns
DOI10.1016/j.jad.2014.09.008
URLView the original
Indexed BySCI
Language英语
WOS Research AreaNeurosciences & Neurology ; Psychiatry
WOS SubjectClinical Neurology ; Psychiatry
WOS IDWOS:000344226700039
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Cited Times [WOS]:2   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Affiliation1.Veterans Administration Ann Arbor Center for Clinical Management Research
2.Shenzhen Mental Health Centre
3.Beijing An Ding Hospital, Capital Medical University
4.Hangzhou Seventh People's Hospital
5.Harbin Medical University
6.Nanjing Medical University
7.University of Michigan Medical School
8.Chinese University of Hong Kong
9.Shanghai Jiao Tong University School of Medicine
10.Peking University Health Science Center
11.Zhejiang University
12.Peking University
13.Sun Yat-Sen University
14.West China Hospital of Sichuan University
15.Second Xiangya Hospital of Central-South University
16.Tongji University
17.University of Notre Dame Australia
18.Universidade de Macau
Recommended Citation
GB/T 7714
Hu C.,Geng Y.,Feng Y.,et al. Demographic and clinical differences between early- and late-onset major depressions in thirteen psychiatric institutions in China[J]. Journal of Affective Disorders,2015,170:266-269.
APA Hu C..,Geng Y..,Feng Y..,Wang G..,Ungvari G.S..,...&Xiang Y.-T..(2015).Demographic and clinical differences between early- and late-onset major depressions in thirteen psychiatric institutions in China.Journal of Affective Disorders,170,266-269.
MLA Hu C.,et al."Demographic and clinical differences between early- and late-onset major depressions in thirteen psychiatric institutions in China".Journal of Affective Disorders 170(2015):266-269.
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