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Antidepressant prescription pattern in the presence of medical co-morbidity: REAP-AD 2013 Study
Grover S.15; Avasthi A.15; Tripathi A.10; Tanra A.J.16; Chee K.Y.3; He Y.L.14; Chiu H.F.K.9; Kuga H.12; Lee M.S.5; Chong M.Y.8; Udormatn P.17; Kanba S.12; Yang S.Y.4; Si T.M.13; Sim K.2; Tan C.H.6; Shen W.W.11; Xiang Y.T.18; Sartorius N.1; Shinfuku N.7
2015-09-01
Source PublicationEast Asian Archives of Psychiatry
ISSN22247041 20789947
Volume25Issue:3Pages:99-107
AbstractObjective: To evaluate the prescription pattern of antidepressants in patients with medical co-morbidity from major psychiatric centres in Asia. Methods: The Research on Asian Psychotropic Prescription Pattern for Antidepressants (REAP-AD 2013) collected data from 42 psychiatric centres in 10 Asian countries and regions. Antidepressant prescriptions of 2320 patients with various psychiatric disorders were evaluated. Of these, 370 patients who had specified medical co-morbidities formed the study cohort. Results: Escitalopram (20%) and mirtazapine (20%) were the most commonly prescribed antidepressants in patients with medical co-morbidity followed by sertraline (16%), trazodone (15%), and paroxetine (12%). Overall, more than half (52%; 247/476) of prescriptions comprised selective serotonin reuptake inhibitors. Slightly less than two-thirds (63%; n = 233) of patients received at least 1 selective serotonin reuptake inhibitor. In addition, 79% of patients were prescribed only 1 antidepressant. The mean number of antidepressants used per patient was 1.25 (standard deviation, 0.56). There were subtle differences in the most preferred antidepressant across medical illnesses such as diabetes mellitus, liver dysfunction, acid peptic disease, and cerebrovascular disease. Differences were also seen in prescription patterns across different countries. Conclusion: Although selective serotonin reuptake inhibitors formed the bulk of antidepressant prescriptions in the presence of medical co-morbidity, mirtazapine was also commonly used in the presence of medical co-morbidities. Specified medical morbidities do influence the selection of antidepressants.
KeywordAntidepressive agents Asia Comorbidity
URLView the original
Language英語
Fulltext Access
Document TypeJournal article
CollectionUniversity of Macau
Affiliation1.Association for the Improvement of Mental Health Programmes
2.Institute of Public Health
3.Kuala Lumpur Hospital
4.Taipei City Hospital Taiwan
5.Korea University
6.National University of Singapore
7.Kobe University
8.Chang Gung University
9.Chinese University of Hong Kong
10.Chhatrapati Shahuji Maharaj Medical University
11.Taipei Medical University
12.Kyushu University
13.Peking University
14.Shanghai Mental Health Center
15.Postgraduate Institute of Medical Education and Research
16.Hasanuddin University
17.Prince of Songkla University
18.Universidade de Macau
Recommended Citation
GB/T 7714
Grover S.,Avasthi A.,Tripathi A.,et al. Antidepressant prescription pattern in the presence of medical co-morbidity: REAP-AD 2013 Study[J]. East Asian Archives of Psychiatry,2015,25(3):99-107.
APA Grover S..,Avasthi A..,Tripathi A..,Tanra A.J..,Chee K.Y..,...&Shinfuku N..(2015).Antidepressant prescription pattern in the presence of medical co-morbidity: REAP-AD 2013 Study.East Asian Archives of Psychiatry,25(3),99-107.
MLA Grover S.,et al."Antidepressant prescription pattern in the presence of medical co-morbidity: REAP-AD 2013 Study".East Asian Archives of Psychiatry 25.3(2015):99-107.
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