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Prescribing pattern of antidepressants in children and adolescents: Findings from the research on Asia psychotropic prescription pattern
Chee K.Y.3; Tripathi A.11; Avasthi A.17; Chong M.Y.5; Xiang Y.T.20; Sim K.13; Kanba S.14; He Y.L.16; Lee M.S.6; Chiu H.F.K.10; Yang S.Y.4; Kuga H.14; Udomratn P.19; Tanra A.J.18; Maramis M.M.9; Grover S.17; Mahendran R.15; Kallivayalil R.A.1; Shen W.W.12; Shinfuku N.8; Tan C.H.7; Sartorius N.2
2016-03-01
Source PublicationEast Asian Archives of Psychiatry
ISSN22247041 20789947
Volume26Issue:1Pages:10-17
AbstractObjective: Pharmacotherapy of depression in children and adolescents is complex. In the absence of research into the efficacy and safety of antidepressants in this group of patients, their off-label prescription is common. This paper aimed to illustrate the prescription pattern of antidepressants in children and adolescents from major psychiatric centres in Asia. Methods: The Research on Asia Psychotropic Prescription Pattern on Antidepressants worked collaboratively in 2013 to study the prescription pattern of antidepressants in Asia using a unified research protocol and questionnaire. Forty psychiatric centres from 10 Asian countries / regions participated and 2321 antidepressant prescriptions were analysed. Results: A total of 4.7% antidepressant prescriptions were for children and adolescents. Fluoxetine, sertraline, and escitalopram were the most common antidepressants prescribed for children and adolescents. Almost one-third (30.3%) of prescriptions were for diagnoses other than depressive and anxiety disorders. There was less antidepressant polypharmacy and concomitant use of benzodiazepine, but more concomitant use of antipsychotics in children and adolescents compared with adults. Conclusion: Off-label use of antidepressants in children and adolescents was reported by 40 Asian psychiatric institutions that participated in the study. In-service education and regulatory mechanisms should be reinforced to ensure efficacy and safety of antidepressants in children and adolescents.
KeywordAdolescent Antidepressive agents Child Ethnopsychology
URLView the original
Language英語
Fulltext Access
Document TypeJournal article
CollectionFaculty of Health Sciences
Affiliation1.Pushpagiri Medical College
2.Association for the Improvement of Mental Health Programmes
3.Kuala Lumpur Hospital
4.Taipei City Hospital Taiwan
5.Chang Gung Memorial Hospital
6.Korea University
7.National University of Singapore
8.Kobe University
9.Universitas Airlangga
10.Chinese University of Hong Kong
11.Chhatrapati Shahuji Maharaj Medical University
12.Taipei Medical University
13.Singapore Institute of Mental Health
14.Kyushu University
15.National University Hospital, Singapore
16.Shanghai Mental Health Center
17.Postgraduate Institute of Medical Education and Research
18.Hasanuddin University
19.Prince of Songkla University
20.Universidade de Macau
Recommended Citation
GB/T 7714
Chee K.Y.,Tripathi A.,Avasthi A.,et al. Prescribing pattern of antidepressants in children and adolescents: Findings from the research on Asia psychotropic prescription pattern[J]. East Asian Archives of Psychiatry,2016,26(1):10-17.
APA Chee K.Y..,Tripathi A..,Avasthi A..,Chong M.Y..,Xiang Y.T..,...&Sartorius N..(2016).Prescribing pattern of antidepressants in children and adolescents: Findings from the research on Asia psychotropic prescription pattern.East Asian Archives of Psychiatry,26(1),10-17.
MLA Chee K.Y.,et al."Prescribing pattern of antidepressants in children and adolescents: Findings from the research on Asia psychotropic prescription pattern".East Asian Archives of Psychiatry 26.1(2016):10-17.
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