UM  > 健康科學學院
Intracranial Atherosclerosis and Poststroke Depression in Chinese Patients with Ischemic Stroke
Chen Y.-K.1; Qu J.-F.1; Xiao W.-M.1; Li W.-Y.1; Li W.1; Fang X.-W.1; Weng H.-Y.1; Liu Y.-L.1; Luo G.-P.1; Ungvari G.S.2; Xiang Y.-T.4
2016-04-01
Source PublicationJournal of Stroke and Cerebrovascular Diseases
ISSN15328511 10523057
Volume25Issue:4Pages:998-1004
Abstract

Background Intracranial atherosclerosis (ICAS) is a common etiology of ischemic stroke in Chinese patients, probably leading to regional hypoperfusion in the brain. The purpose of this prospective study was to investigate the association between ICAS and poststroke depression in Chinese patients with ischemic stroke. Methods During the study period, a total of 569 patients aged between 40 and 80 years with acute ischemic stroke were consecutively admitted and screened. Patients with a National Institutes of Health Stroke Scale (NIHSS) total score of 15 or higher, with severe cognitive impairment, or with a history of depression before stroke were excluded. Two hundred seven patients with ischemic stroke were consecutively recruited in the study. Depressive symptoms were assessed in the acute stage and 3 months after stroke. Poststroke depression was defined as a score of 8 or higher in the 24-item Hamilton Depression Rating Scale. The evaluation of the magnetic resonance imaging scans focused on infarctions, white matter lesions, brain atrophy, and ICAS. Results In the acute stage of stroke, logistic regression revealed that female sex, NIHSS score at admission, prestroke insomnia, and ICAS were significant predictors of poststroke depression. At 3 months after stroke, prestroke insomnia, the Mini-Mental State Examination score and ICAS were significant predictors of poststroke depression. Conclusions ICAS may be a significant independent predictor of poststroke depression in Chinese patients with ischemic stroke.

KeywordCerebrovascular Disease Depression Emotional Disorder Intracranial Atherosclerosis Stroke
DOI10.1016/j.jstrokecerebrovasdis.2015.12.038
URLView the original
Indexed BySCI
Language英语
WOS Research AreaNeurosciences & Neurology ; Cardiovascular System & Cardiology
WOS SubjectNeurosciences ; Peripheral Vascular Disease
WOS IDWOS:000373720200043
Fulltext Access
Citation statistics
Cited Times [WOS]:12   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Affiliation1.Dongguan People's Hospital
2.University of Western Australia
3.University of Notre Dame Australia
4.Universidade de Macau
Recommended Citation
GB/T 7714
Chen Y.-K.,Qu J.-F.,Xiao W.-M.,et al. Intracranial Atherosclerosis and Poststroke Depression in Chinese Patients with Ischemic Stroke[J]. Journal of Stroke and Cerebrovascular Diseases,2016,25(4):998-1004.
APA Chen Y.-K..,Qu J.-F..,Xiao W.-M..,Li W.-Y..,Li W..,...&Xiang Y.-T..(2016).Intracranial Atherosclerosis and Poststroke Depression in Chinese Patients with Ischemic Stroke.Journal of Stroke and Cerebrovascular Diseases,25(4),998-1004.
MLA Chen Y.-K.,et al."Intracranial Atherosclerosis and Poststroke Depression in Chinese Patients with Ischemic Stroke".Journal of Stroke and Cerebrovascular Diseases 25.4(2016):998-1004.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Chen Y.-K.]'s Articles
[Qu J.-F.]'s Articles
[Xiao W.-M.]'s Articles
Baidu academic
Similar articles in Baidu academic
[Chen Y.-K.]'s Articles
[Qu J.-F.]'s Articles
[Xiao W.-M.]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Chen Y.-K.]'s Articles
[Qu J.-F.]'s Articles
[Xiao W.-M.]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.