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The disability rate of 5-year post-stroke and its correlation factors: A national survey in China
Yang Y.1; Shi Y.-Z.1; Zhang N.1; Wang S.1; Ungvari G.S.7; Ng C.H.3; Wang Y.-L.1; Zhao X.-Q.1; Wang Y.-J.1; Wang C.-X.1; Xiang Y.-T.8
2016-11-01
Source PublicationPLoS ONE
ISSN19326203
Volume11Issue:11
Abstract

Few studies on long-term functional outcome have been conducted in post-stroke patients in China. The objective of this study was to conduct a nationwide survey in China to investigate the 5-year prevalence of post-stroke disability and its correlation factors. A total of 893 patients with ischemic stroke were included. Demographic, clinical and neuro-imaging information were collected with standardized instruments that assessed stroke severity, depression, cognitive impairment, stroke recurrence and physical disability. Disability was assessed with the modified Ranking Score (mRS), of which a cutoff score ≤2 indicates disability. Statistical analysis included chi-square tests, two independent samples t-tests, Mann-Whitney U test and multiple logistic regression analysis. The frequency of disability in this study population was 45%. Multivariate analyses revealed that older age, lower education level, previous history of stroke, stroke severity at admission, depression, cognitive impairment at 3 months, and stroke recurrence within 5 years follow up were all significantly associated with post-stroke disability. The disability rate in 5-year post-stroke was high in Chinese patients. Treatment of depression, secondary prevention of stroke and rehabilitation may benefit disabled patients with stroke in China.

DOI10.1371/journal.pone.0165341
URLView the original
Indexed BySCI
Language英语
WOS Research AreaScience & Technology - Other Topics
WOS SubjectMultidisciplinary Sciences
WOS IDWOS:000387615200017
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Cited Times [WOS]:15   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Affiliation1.Beijing Tiantan Hospital
2.Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease
3.University of Melbourne
4.University of Western Australia
5.Capital Medical University, Beijing Institute For Brain Disorders
6.China National Clinical Research Center for Neurological Diseases
7.University of Notre Dame Australia
8.Universidade de Macau
Recommended Citation
GB/T 7714
Yang Y.,Shi Y.-Z.,Zhang N.,et al. The disability rate of 5-year post-stroke and its correlation factors: A national survey in China[J]. PLoS ONE,2016,11(11).
APA Yang Y..,Shi Y.-Z..,Zhang N..,Wang S..,Ungvari G.S..,...&Xiang Y.-T..(2016).The disability rate of 5-year post-stroke and its correlation factors: A national survey in China.PLoS ONE,11(11).
MLA Yang Y.,et al."The disability rate of 5-year post-stroke and its correlation factors: A national survey in China".PLoS ONE 11.11(2016).
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