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Gender differences in attitudes towards antipsychotic medications in patients with schizophrenia
Zhou J.1; Xiang Y.-T.7; Li Q.5; Zhu X.5; Li W.5; Ungvari G.S.4; Ng C.H.3; Ongur D.2; Wang X.5
2016-11-30
Source PublicationPsychiatry Research
ISSN18727123 01651781
Volume245Pages:276-281
Abstract

Non-adherence was more frequent in male than in female psychiatric patients. This multi-center study in China examined the gender difference with regard to attitude towards antipsychotic medications and its associations with socio-demographic variables, insight, and psychopathology. Patients’ basic socio-demographic and clinical data were collected. Psychopathology and insight were measured with the Symptom Checklist-90 (SCL-90) and the Insight and Treatment Attitudes Questionnaire (ITAQ), respectively. Their attitudes towards antipsychotic medications were assessed by two standardized questions. Nearly 39.6% (109/275) males and 31.1% (70/225) females reported negative attitudes towards antipsychotic medications. Binary logistic regression revealed that in males single marital status (OR=2.9, 95% CI=1.3–6.4), rural residence (OR=0.4, 95% CI=0.2–0.7), longer duration of schizophrenia (OR=1.0, 95% CI=1.0–1.1), knowledge of medication (OR=1.5, 95% CI=1.3–1.6) and the SCL-90 hostility subscale (OR=0.9, 95% CI=0.9–1.0) were contributors to negative attitudes. In female patients, knowledge about medications (OR=1.4, 95% CI=1.3–1.6), the SCL-90 somatization (OR=0.8, 95% CI=0.8–0.9) and anxiety (OR=1.1, 95% CI=1.0–1.2) subscales were contributors to negative attitudes. The study suggested that different psychosocial and clinical factors accounted for the negative attitude towards antipsychotic treatment in male and female patients.

KeywordAntipsychotics Attitude Gender Schizophrenia
DOI10.1016/j.psychres.2016.08.041
URLView the original
Indexed BySCI
Language英语
WOS Research AreaPsychiatry
WOS SubjectPsychiatry
WOS IDWOS:000386741600039
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Cited Times [WOS]:6   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Affiliation1.Ministry of Justice, China
2.McLean Hospital
3.University of Melbourne
4.University of Western Australia
5.Second Xiangya Hospital of Central-South University
6.University of Notre Dame Australia
7.Universidade de Macau
Recommended Citation
GB/T 7714
Zhou J.,Xiang Y.-T.,Li Q.,et al. Gender differences in attitudes towards antipsychotic medications in patients with schizophrenia[J]. Psychiatry Research,2016,245:276-281.
APA Zhou J..,Xiang Y.-T..,Li Q..,Zhu X..,Li W..,...&Wang X..(2016).Gender differences in attitudes towards antipsychotic medications in patients with schizophrenia.Psychiatry Research,245,276-281.
MLA Zhou J.,et al."Gender differences in attitudes towards antipsychotic medications in patients with schizophrenia".Psychiatry Research 245(2016):276-281.
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