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Duration of untreated bipolar disorder: A multicenter study
Zhang L.10; Yu X.8; Fang Y.-R.6; Ungvari G.S.11; Ng C.H.2; Chiu H.F.K.5; Li H.-C.7; Yang H.-C.1; Tan Q.-R.9; Xu X.-F.4; Wang G.10; Xiang Y.-T.12
2017-03-22
Source PublicationScientific Reports
ISSN20452322
Volume7
Abstract

Little is known about the demographic and clinical differences between short and long duration of untreated bipolar disorder (DUB) in Chinese patients. This study examined the demographic and clinical features of short (≤2 years) and long DUB (>2 years) in China. A consecutively recruited sample of 555 patients with bipolar disorder (BD) was examined in 7 psychiatric hospitals and general hospital psychiatric units across China. Patients' demographic and clinical characteristics were collected using a standardized protocol and data collection procedure. The mean DUB was 3.2 ± 6.0 years; long DUB accounted for 31.0% of the sample. Multivariate analyses revealed that longer duration of illness, diagnosis of BD type II, and earlier misdiagnosis of BD for major depressive disorder or schizophrenia were independently associated with long DUB. The mean DUB in Chinese BD patients was shorter than the reported figures from Western countries. The long-term impact of DUB on the outcome of BD is warranted.

DOI10.1038/srep44811
URLView the original
Indexed BySCI
WOS Research AreaScience & Technology - Other Topics
WOS SubjectMultidisciplinary Sciences
WOS IDWOS:000397011000001
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Cited Times [WOS]:6   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Affiliation1.Shenzhen Mental Health Centre
2.University of Melbourne
3.University of Western Australia
4.Kunming Medical University
5.Chinese University of Hong Kong
6.Shanghai Jiao Tong University School of Medicine
7.Zhejiang University
8.Peking University
9.Xijing Hospital
10.Capital Medical University, Beijing Institute For Brain Disorders
11.University of Notre Dame Australia
12.Universidade de Macau
Recommended Citation
GB/T 7714
Zhang L.,Yu X.,Fang Y.-R.,et al. Duration of untreated bipolar disorder: A multicenter study[J]. Scientific Reports,2017,7.
APA Zhang L..,Yu X..,Fang Y.-R..,Ungvari G.S..,Ng C.H..,...&Xiang Y.-T..(2017).Duration of untreated bipolar disorder: A multicenter study.Scientific Reports,7.
MLA Zhang L.,et al."Duration of untreated bipolar disorder: A multicenter study".Scientific Reports 7(2017).
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