UM
Pulsatile shear stress and high glucose concentrations induced reactive oxigen species production in endothelial cells
Yu J.Q.; Chin L.K.; Fu Y.; Yu T.; Luo K.Q.; Liu A.Q.
2011-09-01
Source Publication2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
Pages767-770
AbstractA hemodynamic Lab-on-a-chip system was developed in this study. This system has two unique features: (1) it consists of a microfluidic network with an array of endothelial cell seeding sites for testing them under multiple conditions, and (2) the flow rate and the frequency of the culture medium in the microchannel are controlled by a pulsation free pump to mimic the flow profile of the blood in the blood vessel under different physiological conditions. The results demonstrate the advantage of utilizing this system over the conventional non-pulsatile system in the future shear stress related studies. © 2011 IEEE.
Keywordendothelial cell Hemodynamic Lab-on-a-chip reactive oxygen species
DOI10.1109/TRANSDUCERS.2011.5969310
URLView the original
Language英語
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Document TypeConference paper
CollectionUniversity of Macau
AffiliationNanyang Technological University
Recommended Citation
GB/T 7714
Yu J.Q.,Chin L.K.,Fu Y.,et al. Pulsatile shear stress and high glucose concentrations induced reactive oxigen species production in endothelial cells[C],2011:767-770.
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