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Imaging osteoarthritis in the knee joints using x-ray guided diffuse optical tomography
Zhang Q.; Yuan Z.; Sobel E.S.; Jiang H.
2010-12-01
Source PublicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7548
AbstractIn our previous studies, near-infrared (NIR) diffuse optical tomography (DOT) had been successfully applied to imaging osteoarthritis (OA) in the finger joints where significant difference in optical properties of the joint tissues was evident between healthy and OA finger joints. Here we report for the first time that large joints such as the knee can also be optically imaged especially when DOT is combined with x-ray tomosynthesis where the 3D image of the bones from x-ray is incorporated into the DOT reconstruction as spatial a priori structural information. This study demonstrates that NIR light can image large joints such as the knee in addition to finger joints, which will drastically broaden the clinical utility of our x-ray guided DOT technique for OA diagnosis. © 2010 Copyright SPIE - The International Society for Optical Engineering.
Keyworddiffuse optical tomography Joints osteoarthritis x-ray tomosynthesis
DOI10.1117/12.853402
URLView the original
Language英語
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Cited Times [WOS]:1   [WOS Record]     [Related Records in WOS]
Document TypeConference paper
CollectionUniversity of Macau
AffiliationUniversity of Florida
Recommended Citation
GB/T 7714
Zhang Q.,Yuan Z.,Sobel E.S.,et al. Imaging osteoarthritis in the knee joints using x-ray guided diffuse optical tomography[C],2010.
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